Benzamide

Benzamide

SCHEMBL5070344

NC(=O)c1ccc(-c2ccccc2)cc1.NC(=O)c1ccccc1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.76
CYP2C19 P33261 2/20 0.76
HSD17B10 Q99714 2/20 0.76
POLB P06746 1/20 0.76
CYP3A4 P08684 1/20 0.76
PARP1 P09874 1/20 0.76
TSHR P16473 1/20 0.76
RECQL P46063 1/20 0.76
BLM P54132 1/20 0.76
PMP22 Q01453 1/20 0.76
TDP1 Q9NUW8 1/20 0.76
L3MBTL1 Q9Y468 1/20 0.76
MKNK1 Q9BUB5 4/20 0.69
MKNK2 Q9HBH9 3/20 0.69
DHODH Q02127 2/20 0.62
RAB9A P51151 3/20 0.59
NPC1 O15118 2/20 0.59
CTDSP1 Q9GZU7 1/20 0.59
SMN1; SMN2 Q16637 2/20 0.58
WDR5 P61964 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27626919 0.98 MKNK1 (0.71) MAPTCYP2C19HSD17B10POLBCYP3A4
SCHEMBL153199 0.98 MKNK1 (0.71) MAPTCYP2C19HSD17B10POLBCYP3A4
Hydrochloric Acid SCHEMBL7913500 0.95 MKNK1 (0.69) MAPTCYP2C19HSD17B10POLBCYP3A4
Iodide SCHEMBL30131442 0.95 MKNK1 (0.69) MAPTCYP2C19HSD17B10POLBCYP3A4
Biphenyl SCHEMBL659450 0.95 MAPT (0.84) MAPTCYP2C19HSD17B10POLBCYP3A4
Hydrochloric Acid SCHEMBL22441935 0.93 MKNK1 (0.67) MAPTCYP2C19HSD17B10POLBCYP3A4
SCHEMBL27446284 0.91 MKNK1 (0.76) MAPTCYP2C19HSD17B10POLBCYP3A4
Fluoromethane SCHEMBL28145184 0.91 MKNK1 (0.65) MAPTCYP2C19HSD17B10POLBCYP3A4
SCHEMBL22367342 0.90 MKNK1 (0.64) MAPTCYP2C19HSD17B10POLBCYP3A4
Terephthalamide SCHEMBL27486747 0.90 PARP1 (0.94) MAPTCYP2C19HSD17B10POLBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2855558-A2 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS Novomer, Inc. (US) 2015-04-08 EP disclosed
WO-2013177546-A2 POLYCARBONATE POLYOL COMPOSITIONS AND METHODS NOVOMER, INC. (US) 2013-11-28 WO disclosed
WO-2008144514-A2 POLYOL-BASED POLYMERS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2008-11-27 WO disclosed
EP-0938640-A1 BARRIER UNITS AND ARTICLES MADE THEREFROM AlliedSignal Inc. (US) 1999-09-01 EP disclosed
WO-1998021542-A1 BARRIER UNITS AND ARTICLES MADE THEREFROM ALLIEDSIGNAL INC. (US) 1998-05-22 WO disclosed
US-RE30352-E AMIDE OR UREA CONTAINING SALT, SULFURIC ACID, HYDROFLUORIC ACID, OR HALO- OR METHANESULFONIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-07-29 US disclosed