SCHEMBL153199

SCHEMBL153199

NC(=O)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MKNK1 Q9BUB5 4/20 0.71
MKNK2 Q9HBH9 3/20 0.71
MAPT P10636 3/20 0.71
CYP2C19 P33261 2/20 0.71
HSD17B10 Q99714 2/20 0.71
L3MBTL1 Q9Y468 2/20 0.71
POLB P06746 1/20 0.71
CYP3A4 P08684 1/20 0.71
PARP1 P09874 1/20 0.71
TSHR P16473 1/20 0.71
RECQL P46063 1/20 0.71
BLM P54132 1/20 0.71
PMP22 Q01453 1/20 0.71
TDP1 Q9NUW8 1/20 0.71
DHODH Q02127 2/20 0.64
SMN1; SMN2 Q16637 3/20 0.60
WDR5 P61964 1/20 0.60
PLA2G10 O15496 1/20 0.59
PLA2G2A P14555 1/20 0.59
PARP10 Q53GL7 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27626919 1.00 MKNK1 (0.71) MKNK1MKNK2MAPTCYP2C19HSD17B10
Benzamide SCHEMBL5070344 0.98 MAPT (0.76) MKNK1MKNK2MAPTCYP2C19HSD17B10
Iodide SCHEMBL30131442 0.98 MKNK1 (0.69) MKNK1MKNK2MAPTCYP2C19HSD17B10
Hydrochloric Acid SCHEMBL7913500 0.98 MKNK1 (0.69) MKNK1MKNK2MAPTCYP2C19HSD17B10
Hydrochloric Acid SCHEMBL22441935 0.95 MKNK1 (0.67) MKNK1MKNK2MAPTCYP2C19HSD17B10
Fluoromethane SCHEMBL28145184 0.93 MKNK1 (0.65) MKNK1MKNK2MAPTCYP2C19HSD17B10
SCHEMBL27446284 0.93 MKNK1 (0.76) MKNK1MKNK2MAPTCYP2C19HSD17B10
SCHEMBL22367342 0.92 MKNK1 (0.64) MKNK1MKNK2MAPTCYP2C19HSD17B10
Biphenyl SCHEMBL659450 0.92 MAPT (0.84) MKNK1MKNK2MAPTCYP2C19HSD17B10
Trimethylammonium SCHEMBL27980004 0.91 MKNK1 (0.62) MKNK1MKNK2MAPTCYP2C19HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4434 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4646207-A1 COMPOSITIONS FOR HORMONALLY IMPACTED SKIN The Boots Company PLC (GB) 2025-11-12 EP claimed
WO-2025056601-A1 PHARMACEUTICAL COMBINATION PRODUCT COMPRISING KINASE INHIBITOR AND AUTOPHAGY INDUCER AND USES THEREOF DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OEFFENTLICHEN RECHTS (DE) 2025-03-20 WO claimed
CN-119320335-A 4- (Biphenyl-4-formamide) -5-chloro-2-methylbenzene diazonium salt as well as preparation method and application thereof 吉林百纯化学科技有限公司 2025-01-17 CN claimed
CN-119192174-A Novel biphenyl carboxylic FXR agonist, preparation method thereof and application thereof as medicine 广东药科大学 2024-12-27 CN claimed
CN-118994074-A Method for preparing biphenyl-4-formyl kesteride by one-pot method 吉林医药学院 2024-11-22 CN claimed
CN-118955447-A Method for preparing both trityl alcohol and biphenyl-4-formylceride 长春百纯和成医药科技有限公司 2024-11-15 CN claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
WO-2024146869-A1 COMPOSITIONS FOR HORMONALLY IMPACTED SKIN THE BOOTS COMPANY PLC (GB) 2024-07-11 WO claimed
WO-2024114056-A1 COMPOSITE MATERIAL AND PREPARATION METHOD THEREFOR, AND LIGHT-EMITTING DEVICE 广东聚华新型显示研究院 2024-06-06 WO claimed
CN-118119253-A Composite material, preparation method thereof and light-emitting device 广东聚华新型显示研究院 2024-05-31 CN claimed
EP-1001766-A4 COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORP (US) 2001-04-04 EP claimed
WO-2001021577-A2 MELANIN CONCENTRATING HORMONE ANTAGONIST TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-03-29 WO claimed
CN-1261795-A Compounds and methods SMITHKLINE BEECHAM CORP (US) 2000-08-02 CN claimed
WO-2000040239-A1 COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 2000-07-13 WO claimed
EP-1001766-A1 COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 2000-05-24 EP claimed
WO-1999001127-A1 COMPOUNDS AND METHODS SMITHKLINE BEECHAM CORPORATION (US) 1999-01-14 WO claimed
CN-1203235-A New chromene compounds, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1998-12-30 CN claimed
EP-0733048-A1 HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1996-09-25 EP claimed
WO-1995015954-A1 HETEROCYCLIC BIPHENYLYLAMIDES USEFUL AS 5HT1D ANTAGONISTS SMITHKLINE BEECHAM PLC (GB) 1995-06-15 WO claimed
US-4693726-A Process for dyeing or printing cellulose fibers or cellulose blend fibers with pyridinium-triazine reactive dye, axable without alkali HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-15 US claimed