Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 8/20 | 0.64 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | DHODH | Q02127 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27626919 | 0.92 | MKNK1 (0.71) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL153199 | 0.92 | MKNK1 (0.71) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL1002578 | 0.92 | CA2 (0.67) | MKNK1MKNK2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL7913500 | 0.90 | MKNK1 (0.69) | MKNK1MKNK2CA12CA1CA2 | |
| Benzamide SCHEMBL5070344 | 0.90 | MAPT (0.76) | MKNK1MKNK2CA12CA1CA2 | |
| Iodide SCHEMBL30131442 | 0.90 | MKNK1 (0.69) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL2589651 | 0.89 | ERN1 (0.60) | MKNK1MKNK2POLBCYP3A4PARP1 | |
| Hydrochloric Acid SCHEMBL22441935 | 0.88 | MKNK1 (0.67) | MKNK1MKNK2CA12CA1CA2 | |
| Fluoromethane SCHEMBL28145184 | 0.86 | MKNK1 (0.65) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL27446284 | 0.86 | MKNK1 (0.76) | MKNK1MKNK2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049555-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-03-06 | — | — | WO | disclosed |
| CN-115734789-A | Degradant-antibody conjugates and methods of use thereof | 安吉克公司 | 2023-03-03 | — | — | CN | disclosed |
| EP-3700901-A1 | (4-HYDROXYPYRROLIDIN-2-YL)-HETEROCYCLIC COMPOUNDS AND METHODS OF USE THEREOF | Genentech, Inc. (US) | 2020-09-02 | — | — | EP | disclosed |