Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11843960 | 0.97 | CA1 (0.33) | CA1CA2CA9CYP1A2CYP2C9 | |
| SCHEMBL48341 | 0.86 | CYP1A2 (0.35) | CYP1A2CYP2C9HIF1A | |
| SCHEMBL14778702 | 0.86 | — | — | |
| SCHEMBL5586838 | 0.85 | MEN1 (0.41) | CA1CA2CA9 | |
| SCHEMBL5070405 | 0.79 | CA1 (0.36) | CA1CA2CA9CYP1A2CYP2C9 | |
| SCHEMBL431960 | 0.79 | CYP1A2 (0.38) | CA1CA2CA9CYP1A2CYP2C9 | |
| SCHEMBL5697079 | 0.77 | CA1 (0.31) | CA1CA2CA9 | |
| SCHEMBL10403522 | 0.77 | CA1 (0.35) | CA1CA2CA9CYP1A2CYP2C9 | |
| SCHEMBL9513161 | 0.77 | CA1 (0.35) | CA1CA2CA9CYP1A2CYP2C9 | |
| SCHEMBL131595 | 0.74 | ABCB11 (0.41) | CA1CA2CA9CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0439766-A2 | Process for the preparation of N-acyl-4-phenyl-pyrrolidin-2-ones having cerebroprotective activity | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-08-07 | — | — | EP | claimed |
| US-11808750-B2 | Solid-phase sampling device and methods for point-source sampling of polar organic analytes | BATTELLE SAVANNAH RIVER ALLIANCE, LLC (US) | 2023-11-07 | — | — | US | disclosed |
| US-11022593-B2 | Solid phase sampling device and methods for point-source sampling of polar organic analytes | SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (US) | 2021-06-01 | — | — | US | disclosed |
| US-20200132653-A1 | SOLID PHASE SAMPLING DEVICE AND METHODS FOR POINT-SOURCE SAMPLING OF POLAR ORGANIC ANALYTES | BATTELLE SAVANNAH RIVER ALLIANCE, LLC | 2020-04-30 | — | — | US | disclosed |
| EP-1885404-A2 | BIOCONJUGATION REACTIONS FOR ACYLATING POLYETHLENE GLYCOL REAGENTS | Alza Corporation (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20060286657-A1 | Novel bioconjugation reactions for acylating polyethylene glycol reagents | ALZA CORPORATION | 2006-12-21 | — | — | US | disclosed |
| WO-2006130799-A2 | BIOCONJUGATION REACTIONS FOR ACYLATING POLYETHLENE GLYCOL REAGENTS | ALZA CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
| EP-1031629-A2 | Method of preparation of stereoisomeric carboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-30 | — | — | EP | disclosed |
| EP-0439766-A2 | Process for the preparation of N-acyl-4-phenyl-pyrrolidin-2-ones having cerebroprotective activity | ARZNEIMITTELWERK DRESDEN GmbH (DE) | 1991-08-07 | — | — | EP | disclosed |
| US-4914206-A | ANTIBIOTICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1990-04-03 | — | — | US | disclosed |
| US-3936452-A | Process of producing pyrimidyl thiocarbonates | NITTO BOSEKI CO., LTD. (JA) | 1976-02-03 | — | — | US | disclosed |
| US-3932375-A | PROTECTING GROUPS | NITTO BOSEKI CO. LTD. (JA) | 1976-01-13 | — | — | US | disclosed |