SCHEMBL9513161

SCHEMBL9513161

O=C(Cl)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
HIF1A Q16665 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL431960 0.79 CYP1A2 (0.38) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL5070405 0.79 CA1 (0.36) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL5070407 0.77 CA1 (0.35) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL10403522 0.77 CA1 (0.35) CA1CA2CA9CYP1A2CYP2C9
Hydrochloric Acid SCHEMBL11843960 0.74 CA1 (0.33) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL131595 0.74 ABCB11 (0.41) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL27278994 0.74 CA1 (0.39) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL16344199 0.74 CYP1A2 (0.33) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL11233782 0.72 CYP1A2 (0.42) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL6706197 0.72 CYP1A2 (0.42) CA1CA2CA9CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107398188-A Preparation method of nano composite forward osmosis with grafted organosilane multi-walled carbon nano-tube embedded in polyamide separation layer 浙江工业大学 2017-11-28 CN claimed
CN-101502763-B Novel biological contamination-resistant ultrathin compound film and preparation method thereof DEV CT OF WATER TREAT TECHNOLOGY HANGZHOU 2011-06-22 CN claimed
CN-101502763-A Novel biological contamination-resistant ultrathin compound film and preparation method thereof DEV CT OF WATER TREAT TECHNOLO (CN) 2009-08-12 CN claimed
US-4883903-A FROM CHLOROETHYLAMINE, A HALOFORMATE; AND NITROSYL SULFURIC ACID SANOFI (FR) 1989-11-28 US claimed
EP-0038357-A4 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS. UNIV ILLINOIS (US) 1982-03-22 EP claimed
EP-0038357-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS University of Illinois Foundation (US) 1981-10-28 EP claimed
WO-1981001145-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS UNIV ILLINOIS (US) 1981-04-30 WO claimed
CN-107398188-A Preparation method of nano composite forward osmosis with grafted organosilane multi-walled carbon nano-tube embedded in polyamide separation layer 浙江工业大学 2017-11-28 CN disclosed
CN-101502763-B Novel biological contamination-resistant ultrathin compound film and preparation method thereof DEV CT OF WATER TREAT TECHNOLOGY HANGZHOU 2011-06-22 CN disclosed
CN-101502763-A Novel biological contamination-resistant ultrathin compound film and preparation method thereof DEV CT OF WATER TREAT TECHNOLO (CN) 2009-08-12 CN disclosed
EP-0256763-B1 Process for azetidinones UNIV NOTRE DAME DU LAC (US) 1993-12-08 EP disclosed
US-4883903-A FROM CHLOROETHYLAMINE, A HALOFORMATE; AND NITROSYL SULFURIC ACID SANOFI (FR) 1989-11-28 US disclosed
US-4751296-A WITH POSITIVE HALOGEN IN THE PRESENCE OF WEAK BASE UNIVERSITY OF NOTRE DAME DU LAC (US) 1988-06-14 US disclosed
EP-0256763-A1 Process for azetidinones THE UNIVERSITY OF NOTRE DAME DU LAC (US) 1988-02-24 EP disclosed
EP-0038357-A4 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS. UNIV ILLINOIS (US) 1982-03-22 EP disclosed
EP-0038357-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS University of Illinois Foundation (US) 1981-10-28 EP disclosed
WO-1981001145-A1 HYDROLYTIC ENZYME-ACTIVATIBLE PRO-DRUGS UNIV ILLINOIS (US) 1981-04-30 WO disclosed
US-3943126-A Process for acylating a 7-aminocephalosporin ELI LILLY AND COMPANY (US) 1976-03-09 US disclosed