SCHEMBL5070405

SCHEMBL5070405

O=C(Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl)Oc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
HIF1A Q16665 1/20 0.34
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
KMT2A Q03164 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11605744 0.85 PTPN1 (0.31)
SCHEMBL17972599 0.84 KDM4E (0.35) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL431960 0.81 CYP1A2 (0.38) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL11562674 0.80 TDP1 (0.41) MEN1ALDH1A1MAPTHPGDKMT2A
SCHEMBL5070407 0.79 CA1 (0.35) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL10403522 0.79 CA1 (0.35) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL9513161 0.79 CA1 (0.35) CA1CA2CA9CYP1A2CYP2C9
SCHEMBL11602981 0.77 PTK2B (0.44) MEN1LMNAMAPTHPGDTSHR
SCHEMBL11013172 0.77 FABP3 (0.43) CYP1A2CYP2C9HIF1AALDH1A1LMNA
SCHEMBL131595 0.77 ABCB11 (0.41) CA1CA2CA9CYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11808750-B2 Solid-phase sampling device and methods for point-source sampling of polar organic analytes BATTELLE SAVANNAH RIVER ALLIANCE, LLC (US) 2023-11-07 US disclosed
EP-3626702-B1 CARBONATE DERIVATIVE PRODUCTION METHOD UNIV KOBE NAT UNIV CORP (JP) 2023-02-15 EP disclosed
CN-110637006-B Process for producing carbonate derivative 国立大学法人神户大学 2022-05-24 CN disclosed
US-11130728-B2 Carbonate derivative production method NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2021-09-28 US disclosed
US-11022593-B2 Solid phase sampling device and methods for point-source sampling of polar organic analytes SAVANNAH RIVER NUCLEAR SOLUTIONS, LLC (US) 2021-06-01 US disclosed
US-20200132653-A1 SOLID PHASE SAMPLING DEVICE AND METHODS FOR POINT-SOURCE SAMPLING OF POLAR ORGANIC ANALYTES BATTELLE SAVANNAH RIVER ALLIANCE, LLC 2020-04-30 US disclosed
EP-3626702-A1 CARBONATE DERIVATIVE PRODUCTION METHOD National University Corporation Kobe University (JP) 2020-03-25 EP disclosed
US-20200079723-A1 CARBONATE DERIVATIVE PRODUCTION METHOD NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) 2020-03-12 US disclosed
CN-110637006-A Process for producing carbonate derivative 国立大学法人神户大学 2019-12-31 CN disclosed
US-9951179-B2 Cyclic carbonate monomers and ring opened polycarbonates therefrom INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2018-04-24 US disclosed
US-6143917-A FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD UBE INDUSTRIES, LTD. (JP) 2000-11-07 US disclosed
US-6063922-A Carbamate functional 1,3,5-triazines CYTEC TECHNOLOGY CORP. (US) 2000-05-16 US disclosed
EP-0976739-A2 A Process for the preparation of 1,3,5-triazine carbamates, at least biscarbimate functional 1,3,5-triazines as well as use of 1,3,5-triazine carbamates CYTEC TECHNOLOGY CORP. (US) 2000-02-02 EP disclosed
EP-0902014-A1 PROCESS FOR PRODUCING ARYL CARBAMATES UBE INDUSTRIES LIMITED (JP) 1999-03-17 EP disclosed
US-5792866-A Process for the preparation of 1,3,5-triazine carbamates from amino 1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORPORATION (US) 1998-08-11 US disclosed
US-5705641-A Process for the preparation of 1,3,5-triazine carbamates from amino-1,3,5-triazines and organic carbonates CYTEC TECHNOLOGY CORP. (US) 1998-01-06 US disclosed
EP-0624577-A1 Process for the preparation of 1,3,5-triazine carbamates, at least biscarbamate functional 1,3,5-triazines and their use as crosslinkers CYTEC TECHNOLOGY CORP. (US) 1994-11-17 EP disclosed
US-4530933-A 8-Aza-13-thiaprostanoids and a method of use thereof as anti-ulcer agents E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-23 US disclosed
US-3936452-A Process of producing pyrimidyl thiocarbonates NITTO BOSEKI CO., LTD. (JA) 1976-02-03 US disclosed
US-3932375-A PROTECTING GROUPS NITTO BOSEKI CO. LTD. (JA) 1976-01-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200079723-A1 CARBONATE DERIVATIVE PRODUCTION METHOD CA4, CA14, CA3 CA1 12/4885CA2 4/4885CA9 6/4885
US-11130728-B2 Carbonate derivative production method CA4, CA14, CA3 CA1 12/4885CA2 4/4885CA9 6/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.