Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 5/20 | 0.54 |
| ▸ | TRPA1 | O75762 | 8/20 | 0.48 |
| ▸ | MIF | P14174 | 4/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | BACH1 | O14867 | 1/20 | 0.42 |
| ▸ | MAFK | O60675 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1607282 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL1606718 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL1607149 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL1607124 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL14933787 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL25332541 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL2485837 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL14933784 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| SCHEMBL106183 | 1.00 | NAAA (0.54) | NAAATRPA1MIFGSK3BKEAP1 | |
| Sulforaphane SCHEMBL20855320 | 0.98 | NAAA (0.50) | NAAATRPA1MIFGSK3BKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2737897-A2 | Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes | Metaproteomics, LLC (US) | 2014-06-04 | — | — | EP | disclosed |
| US-20130064913-A1 | ANTI-INFLAMMATORY BOTANICAL PRODUCTS FOR THE TREATMENT OF METABOLIC SYNDROME AND DIABETES | METAPROTEOMICS, LLC (US) | 2013-03-14 | — | — | US | disclosed |
| US-8206753-B2 | Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes | METAPROTEOMICS, LLC (US) | 2012-06-26 | — | — | US | disclosed |
| EP-1968559-A2 | ANTI-INFLAMMATORY BOTANICAL PRODUCTS FOR THE TREATMENT OF METABOLIC SYNDROME AND DIABETES | Metaproteomics, LLC (US) | 2008-09-17 | — | — | EP | disclosed |
| US-20070281045-A1 | Anti-inflammatory botanical products for the treatment of metabolic syndrome and diabetes | FORTRESS CREDIT CORP. (AS COLLATERAL AGENT) | 2007-12-06 | — | — | US | disclosed |
| WO-2007070355-A2 | ANTI-INFLAMMATORY BOTANICAL PRODUCTS FOR THE TREATMENT OF METABOLIC SYNDROME AND DIABETES | METAPROTEOMICS, LLC (US) | 2007-06-21 | — | — | WO | disclosed |