SCHEMBL106183

SCHEMBL106183

C[S+]([O-])CCCCCCN=C=S

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 5/20 0.54
TRPA1 O75762 8/20 0.48
MIF P14174 4/20 0.48
GSK3B P49841 1/20 0.46
KEAP1 Q14145 2/20 0.42
NFE2L2 Q16236 2/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
BACH1 O14867 1/20 0.42
MAFK O60675 1/20 0.42
EGFR P00533 1/20 0.42
PTGS2 P35354 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1607282 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL5070755 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL1607124 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL1607149 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL14933784 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL14933787 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL25332541 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL1606718 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
SCHEMBL2485837 1.00 NAAA (0.54) NAAATRPA1MIFGSK3BKEAP1
Sulforaphane SCHEMBL20855320 0.98 NAAA (0.50) NAAATRPA1MIFGSK3BKEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629349-B2 Recognition ability improving agent KINJIRUSHI CO., LTD. (JP) 2026-05-19 US claimed
EP-3820290-B1 FUNGICIDES TO PREVENT AND CONTROL FUNGAL PATHOGENS UNIV LAUSANNE (CH) 2025-07-02 EP claimed
EP-3666277-B1 COMPOSITIONS COMPRISING SULFORAPHANE OR A SULFORAPHANE PRECURSOR AND A MUSHROOM EXTRACT OR POWDER NUTRAMAX LAB INC (US) 2025-05-07 EP claimed
US-12178800-B2 Sulforaphane-melatonin-like compound PERPETUUM VENTURES NV (BE) 2024-12-31 US claimed
US-20240423967-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS ARES TRADING S.A. (CH) 2024-12-26 US claimed
CN-119110723-A Blood flow increasing agent for dorsolateral prefrontal cortex, activating agent for dorsolateral prefrontal cortex, food for increasing blood flow for dorsolateral prefrontal cortex, and food for activating dorsolateral prefrontal cortex 金印株式会社 2024-12-10 CN claimed
US-20240316134-A1 BLOOD FLOW INCREASING AGENT FOR DORSOLATERAL PREFRONTAL CORTEX, DORSOLATERAL PREFRONTAL CORTEX ACTIVATOR, FOOD FOR INCREASING BLOOD FLOW IN DORSOLATERAL PREFRONTAL CORTEX, AND FOOD FOR ACTIVATING DORSOLATERAL PREFRONTAL CORTEX KINJIRUSHI CO., LTD. (JP) 2024-09-26 US claimed
CN-118340268-A Raw material composition of food preparation, preparation method and application thereof 宁波宁瑞生物科技有限公司 2024-07-16 CN claimed
EP-4346861-A1 COMPOSITIONS COMPRISING SULFORAPHANE OR A SULFORAPHANE PRECURSOR AND MORINGA PLANT COMPONENTS NUTRAMAX LABORATORIES, INC. (US) 2024-04-10 EP claimed
US-20240041733-A1 DENTAL CARE COMPOSITION AND METHOD OF PROMOTING CALCIFICATION IN LIVING BODY TISSUE KINJIRUSHI CO., LTD. (JP) 2024-02-08 US claimed
WO-2004052351-A1 NOVEL USE OF LYCOPENE DSM IP ASSETS B.V. (CH) 2004-06-24 WO claimed
US-6737441-B2 PREVENTING OR TREATING PERSISTENT CHRONIC GASTRITIS, ULCERS AND/OR STOMACH CANCER Fahey, Jed W. 2004-05-18 US claimed
CN-1469711-A Treatment of helicobacter with isothiocyanates W 2004-01-21 CN claimed
WO-2003068202-A1 COMPOSITIONS COMPRISING LYCOPENE FOR THE TREATMENT AND PREVENTION OF ANGIOGENESIS ASSOCIATED PATHOLOGIES DSM IP ASSETS B.V. (NL) 2003-08-21 WO claimed
EP-1313377-A2 TREATMENT OF HELICOBACTER WITH ISOTHIOCYANATES Fahey, Jed W. (US) 2003-05-28 EP claimed
US-20030064131-A1 Method for preparing isothiocyanate(s) from cruciferous plant material JAPANESE R AND D ASSOC. FOR NEW FUNCTIONAL FOODS (JP) 2003-04-03 US claimed
US-20020151505-A1 Treatment of helicobacter with isothiocyanates FAHEY, JED W. 2002-10-17 US claimed
US-6465512-B2 BRINGING THE LEUKEMIC CELLS INTO CONTACT WITH A LEUKEMIC CELL GROWTH INHIBITOR WHICH IS A METHYLSULFINYLALKYL ISOTHIOCYANATE REPRESENTED BY THE GENERAL FORMULA CH3-SO-(CH2)N- N HORIZONTAL-LINE C HORIZONTAL-LINE S NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-10-15 US claimed
WO-2002015722-A2 TREATMENT OF HELICOBACTER WITH ISOTHIOCYANATES FAHEY JED W (US) 2002-02-28 WO claimed
US-20020022655-A1 Leukemic cell growth inhibiting method NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2002-02-21 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240423967-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING GLITAZONES AND NRF2 ACTIVATORS PPARG, PPARA, PPARD NAAA 3132/4885TRPA1 230/4885MIF 2014/4885
US-12629349-B2 Recognition ability improving agent TAS2R8, TST, FABP7 NAAA 271/4885TRPA1 790/4885MIF 3298/4885
US-12178800-B2 Sulforaphane-melatonin-like compound MTNR1B, MTNR1A, HNMT NAAA 3508/4885TRPA1 1935/4885MIF 84/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.