Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.71 |
| ▸ | LDHA | P00338 | 1/20 | 0.54 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | BAD | Q92934 | 1/20 | 0.44 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14225351 | 0.85 | WDR5 (0.79) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL14150504 | 0.84 | WDR5 (0.63) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL29458346 | 0.84 | WDR5 (0.79) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL9124028 | 0.84 | WDR5 (0.79) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL895573 | 0.84 | WDR5 (1.00) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL29721418 | 0.84 | WDR5 (1.00) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL14052430 | 0.83 | KEAP1 (0.48) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL28044056 | 0.82 | MYC (0.65) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL14397431 | 0.82 | WDR5 (0.69) | WDR5LDHASOS1ALDH1A1KDM4E | |
| SCHEMBL10789310 | 0.80 | MYC (0.72) | ALDH1A1KDM4EHPGDMYCMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1561743-B1 | COMPOUND PROTECTING AGAINST ULTRAVIOLET | LEAD CHEM CO LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| CN-101175720-A | Novel haloalkyl sulfone substituted compounds useful for the treatment of obesity and diabetes | NOVO NORDISK AS (DK) | 2008-05-07 | — | — | CN | disclosed |
| US-7361785-B2 | Compound protecting against ultraviolet rays | LEAD CHEMICAL CO., LTD. (JP) | 2008-04-22 | — | — | US | disclosed |
| US-20060051303-A1 | Compound protecting against ultraviolet | LEAD CHEMICAL CO., LTD. (JP) | 2006-03-09 | — | — | US | disclosed |
| EP-1561743-A1 | COMPOUND PROTECTING AGAINST ULTRAVIOLET | Lead Chemical Co. Ltd. (JP) | 2005-08-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | COMT, NAA15, NUDC | WDR5 3436/4885LDHA 2726/4885SOS1 2715/4885 |
| US-20060051303-A1 | Compound protecting against ultraviolet | ERCC4, ERCC2, XPA | WDR5 850/4885LDHA 4727/4885SOS1 2224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.