Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.56 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL514870 | 0.88 | KMT2A (0.82) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL8789804 | 0.87 | CYP19A1 (0.67) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL8789896 | 0.82 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL8836555 | 0.82 | CYP1A2 (0.69) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL7430428 | 0.82 | CYP1A2 (1.00) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL10390463 | 0.82 | KDM4E (0.80) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL3153112 | 0.81 | KDM4E (0.72) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| Hydrochloric Acid SCHEMBL7194533 | 0.80 | BLM (1.00) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| Hydrochloric Acid SCHEMBL29651387 | 0.80 | BLM (1.00) | CYP1A2CYP3A4CYP2D6BLMPMP22 | |
| SCHEMBL29336578 | 0.80 | TSHR (0.69) | CYP1A2CYP3A4CYP2D6BLMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7432228-B2 | Inhibitor against biosynthesis of abscisic acid | RIKEN (JP) | 2008-10-07 | — | — | US | disclosed |
| US-7098365-B2 | Abscisic acid biosynthesis inhibitor | RIKEN (JP) | 2006-08-29 | — | — | US | disclosed |
| US-20060148650-A1 | Inhibitor against biosynthesis of abscisic acid | RIKEN (JP) | 2006-07-06 | — | — | US | disclosed |
| US-20050014651-A1 | Abscisic acid biosynthesis inhibitor | RIKEN (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-1439165-A1 | ABSCISIC ACID BIOSYNTHESIS INHIBITOR | Riken (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148650-A1 | Inhibitor against biosynthesis of abscisic acid | COASY, BLVRB, ME1 | CYP1A2 956/4885CYP3A4 3237/4885CYP2D6 2938/4885 |
| US-20050014651-A1 | Abscisic acid biosynthesis inhibitor | COASY, BLVRB, ME1 | CYP1A2 1002/4885CYP3A4 3355/4885CYP2D6 2841/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.