Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.82 |
| ▸ | MEN1 | O00255 | 2/20 | 0.82 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.80 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.80 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.61 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10390463 | 0.94 | KDM4E (0.80) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL5070866 | 0.88 | CYP1A2 (0.69) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8789804 | 0.87 | CYP19A1 (0.67) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL6131892 | 0.86 | MEN1 (0.67) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL4740336 | 0.85 | KDM4E (0.68) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8790689 | 0.85 | KDM4E (0.67) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL14301912 | 0.84 | CYP1A2 (0.77) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8836555 | 0.82 | CYP1A2 (0.69) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| SCHEMBL8789896 | 0.82 | CYP1A2 (0.69) | KMT2AMEN1KDM4ECYP1A2CYP3A4 | |
| Hydrochloric Acid SCHEMBL5097137 | 0.82 | BLM (0.77) | KMT2AMEN1KDM4ECYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598110-B1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | UNILEVER PLC (GB) | 2015-09-02 | — | — | EP | disclosed |
| EP-2598110-A2 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | Unilever PLC (GB) | 2013-06-05 | — | — | EP | disclosed |
| US-8293218-B2 | Skin care compositions comprising substituted monoamines | CONOPCO, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8293218-B2 | Skin care compositions comprising substituted monoamines | CONOPCO, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-8293218-B2 | Skin care compositions comprising substituted monoamines | CONOPCO, INC. (US) | 2012-10-23 | — | — | US | disclosed |
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | CONOPCO, INC., D/B/A UNILEVER (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2012013418-A2 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | UNILEVER PLC (GB) | 2012-02-02 | — | — | WO | disclosed |
| WO-2012013418-A2 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | UNILEVER PLC (GB) | 2012-02-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027699-A1 | SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES | TYR, CUTA, MAOA | KMT2A 593/4885MEN1 3778/4885KDM4E 331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.