SCHEMBL5071691

SCHEMBL5071691

O=C(O)c1ccc2c(C(=O)O)cc3cccnc3c2n1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.50
LMNA P02545 2/20 0.50
KMT2A Q03164 2/20 0.50
MEN1 O00255 1/20 0.50
TET2 Q6N021 2/20 0.48
TET1 Q8NFU7 2/20 0.48
KDM4A O75164 3/20 0.48
L3MBTL1 Q9Y468 3/20 0.48
ALDH1A1 P00352 2/20 0.48
EGLN1 Q9GZT9 2/20 0.48
KDM6B O15054 1/20 0.48
KDM6A O15550 1/20 0.48
TET3 O43151 1/20 0.48
KDM4B O94953 1/20 0.48
KDM5C P41229 1/20 0.48
KDM4D Q6B0I6 1/20 0.48
ALKBH5 Q6P6C2 1/20 0.48
FTO Q9C0B1 1/20 0.48
KDM4C Q9H3R0 1/20 0.48
KDM2A Q9Y2K7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8674711 0.88 KDM4E (0.54) KDM4ELMNAKMT2AMEN1TET2
SCHEMBL679992 0.86 KDM4E (0.60) KDM4ELMNATET2TET1KDM4A
SCHEMBL8674714 0.82 KDM4E (0.50) KDM4ELMNAKMT2AMEN1TET2
SCHEMBL28573404 0.82 ALDH1A1 (0.51) KDM4ELMNAKMT2AMEN1TET2
SCHEMBL5069004 0.81 KDM4E (0.52) KDM4ELMNAKMT2AMEN1TET2
SCHEMBL3930639 0.79 KDM4E (0.66) KDM4ELMNAKMT2AMEN1TET2
SCHEMBL10611260 0.78 KDM4E (0.59) KDM4ELMNAKMT2AMEN1TET2
Ammonia Solution, Strong SCHEMBL31590844 0.78 KDM4E (0.64) KDM4ELMNAKMT2AMEN1TET2
SCHEMBL13350418 0.76 KDM4E (0.49) KDM4ELMNAKMT2AMEN1KDM4A
SCHEMBL3417100 0.75 ALDH1A1 (0.61) KDM4ELMNAKMT2AMEN1TET2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1901363-A1 LUMINESCENT DEVICE AND ELECTROLUMINESCENCE UTILIZING THE SAME Gifu University (JP) 2008-03-19 EP claimed