Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.59 |
| ▸ | KDM4A | O75164 | 2/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.57 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | KDM6A | O15550 | 1/20 | 0.57 |
| ▸ | TET3 | O43151 | 1/20 | 0.57 |
| ▸ | KDM4B | O94953 | 1/20 | 0.57 |
| ▸ | KDM5C | P41229 | 1/20 | 0.57 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.57 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679992 | 0.88 | KDM4E (0.60) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL8674711 | 0.78 | KDM4E (0.54) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL5071691 | 0.78 | KDM4E (0.50) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL10465646 | 0.78 | KDM4E (0.60) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL28463407 | 0.78 | KDM4E (0.74) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL5069000 | 0.77 | KDM4E (0.52) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL5069004 | 0.77 | KDM4E (0.52) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL69673 | 0.77 | KDM4E (0.77) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL9216834 | 0.76 | ALDH1A1 (0.52) | KDM4EKDM4AEGLN1L3MBTL1TET2 | |
| SCHEMBL522958 | 0.76 | MEN1 (0.71) | KDM4EALDH1A1LMNAALOX12GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1988004292-A1 | ANTIPSYCHOTIC AMINO-POLYHYDRO-BENZ-(ISO)QUINOLINES AND INTERMEDIATES | THE UPJOHN COMPANY (US) | 1988-06-16 | — | — | WO | disclosed |