Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | KDM4A | O75164 | 3/20 | 0.51 |
| ▸ | TET2 | Q6N021 | 2/20 | 0.51 |
| ▸ | TET1 | Q8NFU7 | 2/20 | 0.51 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | KDM6A | O15550 | 1/20 | 0.51 |
| ▸ | TET3 | O43151 | 1/20 | 0.51 |
| ▸ | KDM4B | O94953 | 1/20 | 0.51 |
| ▸ | KDM5C | P41229 | 1/20 | 0.51 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.51 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.51 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8674714 | 0.88 | KDM4E (0.50) | KDM4EL3MBTL1KDM4ATET2TET1 | |
| SCHEMBL5071691 | 0.88 | KDM4E (0.50) | KDM4EL3MBTL1KDM4ATET2TET1 | |
| SCHEMBL679992 | 0.86 | KDM4E (0.60) | KDM4EL3MBTL1KDM4ATET2TET1 | |
| SCHEMBL5069004 | 0.81 | KDM4E (0.52) | KDM4EL3MBTL1KDM4ATET2TET1 | |
| SCHEMBL17178165 | 0.81 | KDM4E (0.52) | KDM4EL3MBTL1KDM4ATET2TET1 | |
| SCHEMBL3930639 | 0.79 | KDM4E (0.66) | KDM4EL3MBTL1TET2TET1LMNA | |
| SCHEMBL10611260 | 0.78 | KDM4E (0.59) | KDM4EL3MBTL1KDM4ATET2TET1 | |
| Ammonia Solution, Strong SCHEMBL31590844 | 0.78 | KDM4E (0.64) | KDM4EL3MBTL1TET2TET1LMNA | |
| SCHEMBL17174167 | 0.78 | KDM4E (0.49) | KDM4EL3MBTL1KDM4ATET2TET1 | |
| SCHEMBL5069000 | 0.75 | KDM4E (0.52) | KDM4EL3MBTL1KDM4ATET2TET1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827653-A | COMPLEMENTARY PROBE HYBRIDIZATION AND FORMATION OF A CHELATED LANTHANIDE COMPLEX, WHICH UPON IRRADIATION BY LIGHT, RESULTS IN A CHARACTERISTIC DELAYED LUMINESCENCE EMISSION | ZENECA LIMITED (GB) | 1998-10-27 | — | — | US | claimed |
| EP-0720659-A1 | NUCLEIC ACID DETECTION WITH ENERGY TRANSFER | ZENECA LIMITED (GB) | 1996-07-10 | — | — | EP | claimed |
| WO-1995008642-A1 | NUCLEIC ACID DETECTION WITH ENERGY TRANSFER | ZENECA LIMITED (GB) | 1995-03-30 | — | — | WO | claimed |