Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 6/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.32 |
| ▸ | CASP2 | P42575 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7684377 | 0.87 | EPHX1 (0.47) | EPHX1DNM1EPHX2CASP2 | |
| SCHEMBL7064442 | 0.85 | EPHX1 (0.42) | EPHX1DNM1MMP2MMP1CASP2 | |
| SCHEMBL29055799 | 0.80 | FAAH (0.44) | EPHX1DNM1EPHX2CASP2 | |
| SCHEMBL6830439 | 0.76 | MEN1 (0.42) | EPHX1CA12CA1CA9MMP2 | |
| SCHEMBL18531295 | 0.76 | CA12 (0.48) | EPHX1MCL1DNM1CA12CA1 | |
| SCHEMBL7674452 | 0.76 | FAAH (0.50) | DNM1EPHX2CNR1 | |
| SCHEMBL11221492 | 0.75 | ZDHHC20 (0.47) | EPHX1EPHX2CASP2 | |
| SCHEMBL6109959 | 0.75 | ALDH1A1 (0.36) | MCL1CA12CA9MMP2MMP1 | |
| SCHEMBL965005 | 0.74 | EPHX1 (0.39) | EPHX1DNM1EPHX2 | |
| SCHEMBL1400993 | 0.74 | CA12 (0.40) | CA12CA1CA9MMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1931352-A2 | TLR AGONISTS | The Regents of the University of California Office of Technology Transfer (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007024707-A2 | TLR AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-03-01 | — | — | WO | disclosed |