Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 2/20 | 1.00 |
| ▸ | TSHR | P16473 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.70 |
| ▸ | PRCP | P42785 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5302449 | 0.99 | LMNA (0.98) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| Caramiphen SCHEMBL181285 | 0.83 | PRCP (1.00) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL8107099 | 0.82 | LMNA (0.69) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| Caramiphen SCHEMBL1374820 | 0.82 | ALDH1A1 (1.00) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| Caramiphen SCHEMBL10898559 | 0.82 | PRCP (0.97) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL12273135 | 0.81 | LMNA (0.68) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL7383119 | 0.81 | ALDH1A1 (0.97) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL8107029 | 0.80 | PRCP (0.95) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL8107092 | 0.79 | ALDH1A1 (0.95) | LMNACYP1A2CYP3A4CYP2D6TSHR | |
| Metcaraphen SCHEMBL21507 | 0.79 | PRCP (0.70) | LMNACYP1A2CYP3A4CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10307428-B2 | Therapeutic compositions for diabetic symmetrical polyneuropathy | UNIVERSITY HEALTH NETWORK (CA) | 2019-06-04 | — | — | US | disclosed |
| US-20190046540-A1 | TREATMENTS FOR DIABETIC SYMMETRICAL POLYNEUROPATHY | UNIVERSITY HEALTH NETWORK (CA) | 2019-02-14 | — | — | US | disclosed |
| US-20130267506-A1 | THERAPEUTIC COMPOSITIONS FOR DIABETIC SYMMETRICAL POLYNEUROPATHY | UNIVERSITY OF MANITOBA (CA) | 2013-10-10 | — | — | US | disclosed |
| WO-2012055018-A1 | THERAPEUTIC COMPOSITIONS FOR DIABETIC SYMMETRICAL POLYNEUROPATHY | UNIVERSITY OF MANITOBA (CA) | 2012-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130267506-A1 | THERAPEUTIC COMPOSITIONS FOR DIABETIC SYMMETRICAL POLYNEUROPATHY | CHRNA5, CHRM2, GAP43 | LMNA 2276/4885CYP1A2 3977/4885CYP3A4 4130/4885 |
| US-20190046540-A1 | TREATMENTS FOR DIABETIC SYMMETRICAL POLYNEUROPATHY | CHRNA5, CHRM2, CHRNE | LMNA 1995/4885CYP1A2 3957/4885CYP3A4 3974/4885 |
| US-10307428-B2 | Therapeutic compositions for diabetic symmetrical polyneuropathy | CHRNA5, CHRM2, GAP43 | LMNA 2276/4885CYP1A2 3977/4885CYP3A4 4130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.