Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 15/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 12/20 | 0.60 |
| ▸ | CHRM3 | P20309 | 12/20 | 0.60 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.60 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.60 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10029779 | 0.85 | CHRM2 (0.66) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL15305877 | 0.79 | CHRM2 (0.84) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL28352271 | 0.78 | CHRM2 (0.64) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL29156932 | 0.78 | CHRM2 (0.64) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8309422 | 0.77 | CHRM2 (0.60) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL31256699 | 0.76 | CHRM2 (0.58) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL30712480 | 0.76 | ALDH1A1 (0.64) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Aprofene SCHEMBL2354824 | 0.75 | CHRM2 (1.00) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9588270 | 0.75 | ALDH1A1 (0.68) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL28555859 | 0.75 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012055018-A1 | THERAPEUTIC COMPOSITIONS FOR DIABETIC SYMMETRICAL POLYNEUROPATHY | UNIVERSITY OF MANITOBA (CA) | 2012-05-03 | — | — | WO | disclosed |