Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.66 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.66 |
| ▸ | BCHE | P06276 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | SCN1A | P35498 | 2/20 | 0.47 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14258113 | 0.87 | TSHR (0.53) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL16732083 | 0.87 | TSHR (0.53) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL5072133 | 0.85 | CHRM2 (0.60) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL28485015 | 0.85 | TSHR (0.51) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL28555859 | 0.85 | CHRM2 (0.53) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL8168380 | 0.85 | KCNN4 (0.55) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL28558105 | 0.85 | TSHR (0.54) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL7427036 | 0.84 | TSHR (0.50) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL2418304 | 0.83 | TSHR (0.53) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL2420565 | 0.83 | TSHR (0.53) | CHRM2CHRM4CHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148039-B2 | Crosslinked siloxane outmost layer having aromatic silicon-containing compounds for photoreceptors | XEROX CORPORATION (US) | 2012-04-03 | — | — | US | disclosed |
| US-7803959-B2 | Synthesis of aromatic silicon-containing compounds | XEROX CORPORATION (US) | 2010-09-28 | — | — | US | disclosed |
| US-7803959-B2 | Synthesis of aromatic silicon-containing compounds | XEROX CORPORATION (US) | 2010-09-28 | — | — | US | disclosed |
| US-7795462-B2 | Crosslinked siloxane outmost layer having aromatic silicon-containing compounds for photoreceptors | XEROX CORPORATION (US) | 2010-09-14 | — | — | US | disclosed |
| US-7795462-B2 | Crosslinked siloxane outmost layer having aromatic silicon-containing compounds for photoreceptors | XEROX CORPORATION (US) | 2010-09-14 | — | — | US | disclosed |
| US-7713499-B2 | Fluidized bed reaction apparatus and methods for using the same | XEROX CORPORATION (US) | 2010-05-11 | — | — | US | disclosed |
| US-7713499-B2 | Fluidized bed reaction apparatus and methods for using the same | XEROX CORPORATION (US) | 2010-05-11 | — | — | US | disclosed |
| US-20100035169-A1 | CROSSLINKED SILOXANE OUTMOST LAYER HAVING AROMATIC SILICON-CONTAINING COMPOUNDS FOR PHOTORECEPTORS | XEROX CORPORATION (US) | 2010-02-11 | — | — | US | disclosed |
| US-7632617-B2 | Silane-phenol compound, overcoat formulation, and electrophotographic imaging member | XEROX CORPORATION (US) | 2009-12-15 | — | — | US | disclosed |
| US-7470493-B2 | Imaging member | XEROX CORPORATION (US) | 2008-12-30 | — | — | US | disclosed |
| US-20070254222-A1 | FLUIDIZED BED REACTION APPARATUS AND METHODS FOR USING THE SAME | XEROX CORPORATION (US) | 2007-11-01 | — | — | US | disclosed |
| US-20070238039-A1 | SYNTHESIS OF AROMATIC SILICON-CONTAINING COMPOUNDS | XEROX CORPORATION (US) | 2007-10-11 | — | — | US | disclosed |
| US-20070238039-A1 | SYNTHESIS OF AROMATIC SILICON-CONTAINING COMPOUNDS | XEROX CORPORATION (US) | 2007-10-11 | — | — | US | disclosed |
| US-20070020540-A1 | Silane-phenol compound, overcoat formulation, and electrophotographic imaging member | XEROX CORPORATION | 2007-01-25 | — | — | US | disclosed |
| US-20070020540-A1 | Silane-phenol compound, overcoat formulation, and electrophotographic imaging member | XEROX CORPORATION | 2007-01-25 | — | — | US | disclosed |
| US-20070020539-A1 | Imaging member | XEROX CORPORATION | 2007-01-25 | — | — | US | disclosed |
| US-20070020539-A1 | Imaging member | XEROX CORPORATION | 2007-01-25 | — | — | US | disclosed |
| US-20070015072-A1 | Imaging members | XEROX CORPORATION | 2007-01-18 | — | — | US | disclosed |
| US-20070015072-A1 | Imaging members | XEROX CORPORATION | 2007-01-18 | — | — | US | disclosed |
| EP-1744220-A2 | Imaging Members | Xerox Corporation (US) | 2007-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070020540-A1 | Silane-phenol compound, overcoat formulation, and electrophotographic imaging member | ARNT, STUB1, FLOT1 | CHRM2 2174/4885CHRM4 1720/4885CHRM1 2817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.