Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3145862 | 0.83 | THRA (0.40) | THRBTHRA | |
| SCHEMBL3137690 | 0.83 | THRA (0.38) | THRBTHRA | |
| SCHEMBL3127279 | 0.82 | THRA (0.41) | THRBTHRA | |
| SCHEMBL3137173 | 0.81 | THRA (0.51) | THRBTHRA | |
| Glycine SCHEMBL5076583 | 0.81 | THRA (0.38) | THRBTHRA | |
| SCHEMBL5072169 | 0.80 | THRA (0.34) | THRBTHRA | |
| SCHEMBL5073545 | 0.77 | THRA (0.35) | THRBTHRA | |
| SCHEMBL5072172 | 0.75 | THRA (0.33) | THRBTHRA | |
| SCHEMBL5076587 | 0.73 | THRA (0.36) | THRBTHRA | |
| SCHEMBL3137145 | 0.73 | THRB (0.41) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899309-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003419-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2007-01-11 | — | — | WO | disclosed |