Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | GBA1 | P04062 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069543 | 0.79 | CYP19A1 (0.50) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL28355465 | 0.78 | LMNA (0.51) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL11638101 | 0.78 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6378337 | 0.78 | MEN1 (0.44) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL30216763 | 0.73 | P2RX1 (0.69) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL28575104 | 0.73 | P2RX1 (0.69) | MEN1KMT2AALDH1A1LMNATDP1 | |
| SCHEMBL16197808 | 0.73 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL6069337 | 0.72 | ALDH1A1 (0.69) | MEN1KMT2AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL1702972 | 0.71 | MEN1 (0.78) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL4166954 | 0.70 | MEN1 (0.65) | MEN1KMT2AALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1319231-A4 | PROGRAMMABLE MOLECULAR DEVICE | UNIV WM MARSH RICE (US) | 2008-11-19 | — | — | EP | disclosed |
| EP-1319231-A1 | PROGRAMMABLE MOLECULAR DEVICE | Wm. MARSH RICE UNIVERSITY (US) | 2003-06-18 | — | — | EP | disclosed |
| US-20030058697-A1 | Programmable molecular device | NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA OFFICE OF NAVAL RESEARCH | 2003-03-27 | — | — | US | disclosed |
| WO-2002009117-A1 | PROGRAMMABLE MOLECULAR DEVICE | WM. MARSH RICE UNIVERSITY (US) | 2002-01-31 | — | — | WO | disclosed |