Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | ALPL | P05186 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALPI | P09923 | 1/20 | 0.54 |
| ▸ | ALPG | P10696 | 1/20 | 0.54 |
| ▸ | APEX1 | P27695 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MPO | P05164 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1893743 | 0.85 | KDM4E (0.68) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL21638087 | 0.83 | ALDH1A1 (0.50) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL12254094 | 0.79 | ALDH1A1 (0.61) | KDM4EALDH1A1MAPTLMNABLM | |
| SCHEMBL31148957 | 0.79 | KDM4E (0.56) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL1364607 | 0.77 | MPO (0.61) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL25286067 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL21638084 | 0.76 | KDM4E (0.64) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL4447450 | 0.76 | PRSS1 (0.42) | MAPTL3MBTL1BLMPOLBRECQL | |
| SCHEMBL11341058 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL1975230 | 0.76 | KDM4E (0.58) | KDM4EALDH1A1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309730-B1 | NEW HYDRAZIDE BUILDING BLOCKS AND HYDRAZIDE MODIFIED BIOMOLECULES | NANOGEN RECOGNOMICS GMBH (DE) | 2008-11-26 | — | — | EP | disclosed |
| US-7129229-B2 | Hydrazide building blocks and hydrazide modified biomolecules | NANOGEN RECOGNOMICS GMBH (DE) | 2006-10-31 | — | — | US | disclosed |
| US-20040087807-A1 | Macromolecules having hydrazide attachment moieties and reagents for their production | SANOFI-AVENTIS S.A. (FR) | 2004-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087807-A1 | Macromolecules having hydrazide attachment moieties and reagents for their production | DNPEP, HPSE, HLCS | KDM4E 2152/4885ALDH1A1 333/4885MAPT 2150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.