Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28484635 | 0.85 | TDP1 (0.51) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL6384289 | 0.82 | TDP1 (0.52) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL1427400 | 0.81 | TDP1 (0.56) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL316676 | 0.79 | NAAA (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL146245 | 0.79 | POLB (0.55) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL13901213 | 0.78 | TDP1 (0.49) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL7107538 | 0.78 | TSHR (0.67) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL28476399 | 0.78 | TSHR (0.67) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL18990497 | 0.78 | TSHR (0.67) | TDP1POLBAPEX1HTTTSHR | |
| SCHEMBL28154418 | 0.78 | TSHR (0.67) | TDP1POLBAPEX1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1323775-B1 | DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION | JSR CORP (JP) | 2008-04-30 | — | — | EP | disclosed |
| EP-1205506-B1 | Rubber composition and methods for producing the same | JSR CORP (JP) | 2004-12-29 | — | — | EP | disclosed |
| US-6740700-B2 | KNEADING FORMULATION COMPRISING A RUBBER COMPONENT CONTAINING CONJUGATED DIENE-BASED RUBBER AND A SILICA; KNEADING SILANE COUPLING AGENT AND FIRST RUBBER, KNEADING SECOND RUBBER FORMULATION, ZINC OXIDE AND VULCANIZING AGENT | JSR CORPORATION (JP) | 2004-05-25 | — | — | US | disclosed |
| US-20040030027-A1 | Diene rubber/inorganic compound composite and method for producing the same and rubber composition | BRIDGESTONE CORPORATION (JP) | 2004-02-12 | — | — | US | disclosed |
| EP-1323775-A1 | DIENE RUBBER/INORGANIC COMPOUND COMPOSITE AND METHOD FOR PRODUCING THE SAME AND RUBBER COMPOSITION | JSR Corporation (JP) | 2003-07-02 | — | — | EP | disclosed |
| US-20020082334-A1 | Rubber composition and methods for producing the same | JSR CORPORATION (JP) | 2002-06-27 | — | — | US | disclosed |