Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384289 | 0.97 | TDP1 (0.52) | NAAATDP1HTTPOLBAPEX1 | |
| SCHEMBL316845 | 0.91 | THRB (0.54) | TDP1HTTPOLBAPEX1ALDH1A1 | |
| SCHEMBL488918 | 0.89 | THRB (0.53) | NAAATDP1HTTPOLBAPEX1 | |
| Methacrylic Acid SCHEMBL28158161 | 0.88 | THRB (0.51) | TDP1HTTPOLBAPEX1ALDH1A1 | |
| SCHEMBL10886447 | 0.87 | LMNA (0.54) | TDP1HTTPOLBAPEX1ALDH1A1 | |
| SCHEMBL8016861 | 0.85 | THRB (0.49) | TDP1HTTPOLBAPEX1ALDH1A1 | |
| Ethylene Glycol SCHEMBL1088568 | 0.85 | ALDH1A1 (0.49) | TDP1HTTPOLBAPEX1ALDH1A1 | |
| SCHEMBL8067939 | 0.85 | ALDH1A1 (0.49) | TDP1HTTPOLBAPEX1ALDH1A1 | |
| SCHEMBL31202591 | 0.84 | TDP1 (0.51) | TDP1HTTPOLBAPEX1ALDH1A1 | |
| SCHEMBL148938 | 0.83 | LMNA (0.60) | TDP1HTTPOLBAPEX1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | ALCON INC (CH) | 2026-01-01 | — | — | US | claimed |
| US-12379611-B2 | Diffractive contact lenses | ALCON INC. (CH) | 2025-08-05 | — | — | US | claimed |
| EP-4121802-B1 | HIGH REFRACTIVE INDEX SILOXANE INSERT MATERIALS FOR EMBEDDED CONTACT LENSES | ALCON INC (CH) | 2024-07-17 | — | — | EP | claimed |
| US-20240142665-A1 | OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2024-05-02 | — | — | US | claimed |
| EP-4356169-A1 | MULTIFOCAL DIFFRACTIVE SILICONE HYDROGEL CONTACT LENSES | Alcon Inc. (CH) | 2024-04-24 | — | — | EP | claimed |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2024-04-11 | — | — | US | claimed |
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| EP-4284787-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-12-06 | — | — | EP | claimed |
| EP-4263513-A1 | OPTICALLY ACTIVE DEVICES | AMO Ireland (IE) | 2023-10-25 | — | — | EP | claimed |
| US-11618823-B2 | High refractive index siloxane insert materials for embedded contact lenses | ALCON INC. (CH) | 2023-04-04 | — | — | US | claimed |
| EP-1210380-B1 | FOLDABLE OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON INC (CH) | 2005-03-16 | — | — | EP | claimed |
| US-6723815-B2 | INTRAOCULAR LENSES AND CONTACT LENSES; HYDROPHOBIC ARYL ACRYLIC MONOMER, A HYDROPHILIC MONOMER SELECTED FROM HYDROXYALKYL (METH)ACRYLATES, N-VINYL PYRROLIDONE AND ACRYLAMIDES, AND A REACTIVE PLASTICIZER | ALCON, INC. (CH) | 2004-04-20 | — | — | US | claimed |
| US-6653422-B2 | Crosslinked acrylic ester copolymer; ultraviolet and blue light absorbers; contact lenses, keratoprostheses, corneal inlays or rings; otological ventilation tubes and nasal implants; intraocular lenses | ALCON UNIVERSAL LTD. (CH) | 2003-11-25 | — | — | US | claimed |
| US-20030208013-A1 | Covalently-bound, hydrophilic coating compositions for surgical implants | ALCON INC. (CH) | 2003-11-06 | — | — | US | claimed |
| US-20030130460-A1 | Foldable ophthalmic and otorhinolaryngological device materials | ALCON INC. (CH) | 2003-07-10 | — | — | US | claimed |
| US-6528602-B1 | Intraocular lens; phenylalkyl methacrylate monomers; crosslinking agent is an methacrylated polyoxyethylene glycol | ALCON UNIVERSAL LTD. (CH) | 2003-03-04 | — | — | US | claimed |
| EP-1210381-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | Alcon Universal, Ltd. (CH) | 2002-06-05 | — | — | EP | claimed |
| EP-1210380-A1 | FOLDABLE OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | Alcon Universal, Ltd. (CH) | 2002-06-05 | — | — | EP | claimed |
| WO-2001018078-A1 | FOLDABLE OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON UNIVERSAL LTD. (CH) | 2001-03-15 | — | — | WO | claimed |
| WO-2001018079-A1 | OPHTHALMIC AND OTORHINOLARYNGOLOGICAL DEVICE MATERIALS | ALCON UNIVERSAL LTD. (CH) | 2001-03-15 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260003210-A1 | DIFFRACTIVE CONTACT LENSES | LBR, CRYZ, CRYAA | NAAA 4171/4885TDP1 2489/4885HTT 3394/4885 |
| US-20240117092-A1 | OPTICALLY ACTIVE DEVICES | PDE6C, UACA, PDE6A | NAAA 1636/4885TDP1 2838/4885HTT 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.