⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27660061 | 0.81 | — | — | |
| SCHEMBL335264 | 0.77 | — | — | |
| SCHEMBL1639997 | 0.77 | — | — | |
| Hydrochloric Acid SCHEMBL3117520 | 0.75 | — | — | |
| SCHEMBL2088409 | 0.75 | — | — | |
| SCHEMBL13221313 | 0.75 | — | — | |
| SCHEMBL155863 | 0.75 | — | — | |
| SCHEMBL1274373 | 0.75 | — | — | |
| SCHEMBL464607 | 0.75 | — | — | |
| SCHEMBL281998 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1007517-B1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | ABBOTT LAB (US) | 2003-10-08 | — | — | EP | claimed |
| EP-1007517-A1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | Abbott Laboratories (US) | 2000-06-14 | — | — | EP | claimed |
| US-5959118-A | Process for the preparation of 5-hydroxymethylthiazoles | ABBOTT LABORATORIES (US) | 1999-09-28 | — | — | US | claimed |
| WO-1999011636-A1 | PROCESS FOR THE PREPARATION OF 5-HYDROXYMETHYLTHIAZOLES | ABBOTT LABORATORIES (US) | 1999-03-11 | — | — | WO | claimed |
| CN-121202808-A | Method for synthesizing 2-chloro-5-chloromethylthiazole and/or 2-chloro-5-bromomethylthiazole based on continuous flow photoreaction | 华东师范大学 | 2025-12-26 | — | — | CN | disclosed |
| CN-121202808-A | Method for synthesizing 2-chloro-5-chloromethylthiazole and/or 2-chloro-5-bromomethylthiazole based on continuous flow photoreaction | 华东师范大学 | 2025-12-26 | — | — | CN | disclosed |
| CN-115785080-B | Uracil parent nucleus compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2024-10-11 | — | — | CN | disclosed |
| CN-115785080-A | Uracil parent nucleus compound and preparation method and application thereof | 陕西盘龙药业集团股份有限公司 | 2023-03-14 | — | — | CN | disclosed |
| CN-110684080-B | scFv-ELISA kit suitable for thiamethoxam residue analysis | 中国农业大学 | 2021-01-15 | — | — | CN | disclosed |
| CN-110684080-A | scFv-ELISA kit suitable for thiamethoxam residue analysis | 中国农业大学 | 2020-01-14 | — | — | CN | disclosed |
| CN-109485644-A | A kind of substituted benzo isothiazole compound and preparation method thereof and purposes | 山东省联合农药工业有限公司 | 2019-03-19 | — | — | CN | disclosed |
| CN-107417682-A | A kind of substituted benzo isothiazole compound and purposes | 山东省联合农药工业有限公司 | 2017-12-01 | — | — | CN | disclosed |
| US-20040162285-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-08-19 | — | — | US | disclosed |
| CN-1516705-A | Novel arylfructose-1, 6-bisphosphatase inhibitors | ֢�����ƹ�˾ | 2004-07-28 | — | — | CN | disclosed |
| WO-2004041818-A1 | ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20040097492-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-20 | — | — | US | disclosed |
| US-20040087577-A1 | Anti-infective agents | ABBOTT LABORATORIES | 2004-05-06 | — | — | US | disclosed |
| US-6265585-B1 | REACTING 2-CHLORO-5-HYDROXYMETHYLTHIAZOLE WITH SULFONYLATING AGENT | SYNGENTA CROP PROTECTION, INC. | 2001-07-24 | — | — | US | disclosed |
| EP-0958286-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | Novartis AG (CH) | 1999-11-24 | — | — | EP | disclosed |
| WO-1998032747-A1 | PROCESS FOR THE PREPARATION OF THIAZOLE DERIVATIVES | NOVARTIS AG (CH) | 1998-07-30 | — | — | WO | disclosed |