Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141250 | 0.89 | THRA (0.37) | THRATHRBPPARG | |
| Propionic Acid SCHEMBL5074391 | 0.89 | THRA (0.35) | THRATHRBPPARG | |
| SCHEMBL3133494 | 0.82 | THRA (0.38) | THRATHRBPPARG | |
| SCHEMBL3140929 | 0.81 | THRA (0.43) | THRATHRBPPARG | |
| SCHEMBL5077541 | 0.77 | THRA (0.33) | THRATHRB | |
| SCHEMBL3142284 | 0.77 | THRB (0.34) | THRATHRBPPARG | |
| SCHEMBL3140915 | 0.76 | THRA (0.38) | THRATHRBPPARG | |
| SCHEMBL3145925 | 0.73 | THRA (0.45) | THRATHRBPPARG | |
| SCHEMBL3145653 | 0.72 | THRA (0.48) | THRATHRBPPARG | |
| SCHEMBL3127311 | 0.71 | THRA (0.45) | THRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1899309-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2008-03-19 | — | — | EP | disclosed |
| WO-2007003419-A1 | HETEROCYCLIC COMPOUNDS AS AGONISTS FOR THE THYROID RECEPTOR | KARO BIO AB (SE) | 2007-01-11 | — | — | WO | disclosed |