Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 3/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 8/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL131702 | 0.87 | — | — | |
| Water SCHEMBL7137776 | 0.85 | TAAR1 (0.53) | FDPSTAAR1HTR1ATBXAS1ALOX15 | |
| Hydrochloric Acid SCHEMBL27603215 | 0.85 | — | — | |
| SCHEMBL28328569 | 0.85 | — | — | |
| Iodide SCHEMBL633203 | 0.85 | — | — | |
| Ethane SCHEMBL28080795 | 0.85 | — | — | |
| Phosphoric Acid SCHEMBL25270783 | 0.85 | FDPS (0.53) | FDPSTAAR1HTR1ATBXAS1ALOX15 | |
| Acetic Acid SCHEMBL27984534 | 0.84 | TAAR1 (0.50) | FDPSTAAR1HTR1ATBXAS1ALOX15 | |
| Urea SCHEMBL28173986 | 0.84 | TAAR1 (0.50) | FDPSTAAR1HTR1ATBXAS1ALOX15 | |
| Bromide SCHEMBL31297775 | 0.83 | TAAR1 (0.52) | FDPSTAAR1HTR1ATBXAS1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114272956-A | ZSM-5 molecular sieve catalyst loaded with ionic liquid and preparation method and application thereof | 河南省化工研究所有限责任公司 | 2022-04-05 | — | — | CN | claimed |
| CN-114272956-A | ZSM-5 molecular sieve catalyst loaded with ionic liquid and preparation method and application thereof | 河南省化工研究所有限责任公司 | 2022-04-05 | — | — | CN | disclosed |
| US-7329715-B2 | Abrasion resistant coatings by siloxane oligomers | YAZAKI CORPORATION (JP) | 2008-02-12 | — | — | US | disclosed |
| US-20060235178-A1 | Abrasion resistant coatings by siloxane oligomers | STOWE WOODWARD LLC | 2006-10-19 | — | — | US | disclosed |
| EP-1203781-B1 | 2-phenylimidazole-phosphoric acid salt as an accelerator for acid anhydride curatives in one-component epoxy compositions | AIR PROD & CHEM (US) | 2005-04-27 | — | — | EP | disclosed |
| US-6462164-B1 | OFFERS A GOOD BALANCE OF LOW-TEMPERATURE CURE AND SHELF STABILITY | AIR PRODUCTS AND CHEMICAL, INC. | 2002-10-08 | — | — | US | disclosed |
| EP-1203781-A1 | 2-phenylimidazole-phosphoric acid salt as an accelerator for acid anhydride curatives in one-component epoxy compositions | AIR PRODUCTS AND CHEMICALS, INC. (US) | 2002-05-08 | — | — | EP | disclosed |