Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoguanine SCHEMBL134675 | 0.85 | ABL1 (0.53) | ABL1RIN1ADORA3USP2ALDH1A1 | |
| Isoguanine SCHEMBL8591970 | 0.83 | ABL1 (0.51) | ABL1RIN1ADORA3USP2ALDH1A1 | |
| Isoguanine SCHEMBL10996058 | 0.78 | ABL1 (0.46) | ABL1RIN1ADORA3USP2ALDH1A1 | |
| Isoguanine SCHEMBL28284042 | 0.75 | ABL1 (0.44) | ABL1RIN1ADORA3USP2ALDH1A1 | |
| Isoguanine SCHEMBL7718191 | 0.75 | ADORA3 (0.41) | ABL1RIN1ADORA3USP2ALDH1A1 | |
| SCHEMBL38551 | 0.71 | — | — | |
| Isoguanine SCHEMBL22660141 | 0.69 | PI4KA (0.39) | ABL1RIN1ADORA3USP2ALDH1A1 | |
| SCHEMBL4302331 | 0.69 | — | — | |
| SCHEMBL23607957 | 0.66 | ABL1 (0.46) | ABL1RIN1ADORA3USP2ALDH1A1 | |
| SCHEMBL23607956 | 0.63 | ABL1 (0.42) | ABL1RIN1ADORA3USP2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919930-A2 | NEW NUCLEIC ACID BASE PAIRS | Dako Denmark A/S (DK) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007045998-A2 | NEW NUCLEIC ACID BASE PAIRS | DAKO DENMARK A/S (US) | 2007-04-26 | — | — | WO | disclosed |