Isoguanine

Isoguanine

SCHEMBL7718191

Nc1nc(=O)[nH]c2nc[nH]c12.Nc1nccc(=O)[nH]1

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 3/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
TP53 P04637 1/20 0.41
HPGD P15428 1/20 0.41
PTGS1 P23219 1/20 0.41
MAPK3 P27361 1/20 0.41
XDH P47989 1/20 0.41
HBB P68871 1/20 0.41
PAX8 Q06710 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ABL1 P00519 1/20 0.41
RIN1 Q13671 1/20 0.41
PNP P00491 1/20 0.38
GDA Q9Y2T3 2/20 0.37
ACHE P22303 1/20 0.37
FGFR1 P11362 1/20 0.36
FLT1 P17948 1/20 0.36
PDPK1 O15530 1/20 0.34
TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isoguanine SCHEMBL134675 0.85 ABL1 (0.53) ADORA3USP2ALDH1A1TP53HPGD
Isoguanine SCHEMBL8591970 0.83 ABL1 (0.51) ADORA3USP2ALDH1A1TP53HPGD
Isoguanine SCHEMBL28284042 0.78 ABL1 (0.44) ADORA3USP2ALDH1A1TP53HPGD
Isoguanine SCHEMBL10996058 0.78 ABL1 (0.46) ADORA3USP2ALDH1A1TP53HPGD
Isoguanine SCHEMBL5074780 0.75 ABL1 (0.41) ADORA3USP2ALDH1A1TP53HPGD
SCHEMBL4825 0.74
Isoguanine SCHEMBL22660141 0.69 PI4KA (0.39) ADORA3USP2ALDH1A1TP53HPGD
SCHEMBL23607957 0.66 ABL1 (0.46) ADORA3USP2ALDH1A1TP53HPGD
Guanine SCHEMBL28026510 0.66 ADORA3 (0.59) ADORA3USP2ALDH1A1TP53HPGD
Guanine SCHEMBL342789 0.65 ADORA3 (0.62) ADORA3USP2ALDH1A1TP53HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1183102-A1 THE USE OF MICROFLUIDIC SYSTEMS IN THE ELECTROCHEMICAL DETECTION OF TARGET ANALYTES Clinical Micro Sensors, Inc. (US) 2002-03-06 EP disclosed
WO-2000062931-A1 THE USE OF MICROFLUIDIC SYSTEMS IN THE ELECTROCHEMICAL DETECTION OF TARGET ANALYTES CLINICAL MICRO SENSORS, INC. (US) 2000-10-26 WO disclosed