SCHEMBL5074995

SCHEMBL5074995

CCCCO[PH](=O)OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
TSHR P16473 3/20 0.49
TDP1 Q9NUW8 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CYP3A4 P08684 1/20 0.49
MAPK1 P28482 1/20 0.49
CETP P11597 3/20 0.43
HPGD P15428 1/20 0.41
LTA4H P09960 2/20 0.41
AR P10275 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HDAC3 O15379 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11364543 0.93 CETP (0.48) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
Butane SCHEMBL9066594 0.87 TSHR (0.44) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL29806030 0.83 TSHR (0.52) ALDH1A1TSHRTDP1L3MBTL1MAPK1
Benzene SCHEMBL8854020 0.83 LTA4H (0.39) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL36370 0.83 TSHR (0.52) ALDH1A1TSHRTDP1L3MBTL1MAPK1
SCHEMBL13444671 0.82 ALDH1A1 (0.53) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL6054451 0.82 TSHR (0.43) ALDH1A1TSHRTDP1L3MBTL1MAPK1
Chlorobenzene SCHEMBL11374111 0.81 LTA4H (0.42) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL27497307 0.81 ALDH1A1 (0.55) ALDH1A1TSHRTDP1L3MBTL1CYP3A4
SCHEMBL8733833 0.79 TSHR (0.50) ALDH1A1TSHRTDP1L3MBTL1LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507851-B2 Halocombstatins and methods of synthesis thereof ARIZONA BOARD OF REGENTS, A STATE CORPORATE OF THE STATE OF ARIZONA, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2009-03-24 US disclosed
EP-1888705-A1 REVERSIBLY THERMOCHROMIC COMPOSITIONS Ciba Specialty Chemicals Holding, Inc. (CH) 2008-02-20 EP disclosed
WO-2006131465-A1 REVERSIBLY THERMOCHROMIC COMPOSITIONS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-12-14 WO disclosed
US-4168357-A Preparation of high cis-1,4-polypentadiene THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-09-18 US disclosed
US-4168374-A POLYMERIZATION OF PENTADIENE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-09-18 US disclosed
US-4148983-A TERTIARY CATALYST SYSTEM INCLUDING AN ORGANOMETALLIC COMPOUND, A CHROMIUM COMPOUND AND AN ORGANIC PHOSPHITE THE GOODYEAR TIRE & RUBBER COMPANY (US) 1979-04-10 US disclosed