SCHEMBL5075153

SCHEMBL5075153

CCOCC(CO[Si](C)(C)C)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ALDH1A1 P00352 5/20 0.33
RECQL P46063 1/20 0.33
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
MMP8 P22894 1/20 0.33
TP53 P04637 1/20 0.32
TSHR P16473 2/20 0.31
RAB9A P51151 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
HSD17B10 Q99714 1/20 0.30
TRPA1 O75762 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5081776 0.90 SLC6A2 (0.42) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL1791345 0.88 SLC6A2 (0.43) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL5081430 0.88 SLC6A2 (0.33) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL5077632 0.88 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6TP53
SCHEMBL5080932 0.86 SLC6A2 (0.36) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL5081653 0.86 SLC6A2 (0.33) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL5077300 0.86 ALDH1A1 (0.33) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL5080799 0.86 SLC6A2 (0.34) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL5080806 0.85 ALDH1A1 (0.33) SLC6A2TAAR1ALDH1A1RECQLLMNA
SCHEMBL5081544 0.84 SLC6A2 (0.33) SLC6A2TAAR1ALDH1A1RECQLLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed