SCHEMBL5077632

SCHEMBL5077632

CCCOCC(CO[Si](C)(C)C)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.33
TAAR1 Q96RJ0 1/20 0.33
LMNA P02545 1/20 0.32
CYP2D6 P10635 1/20 0.32
TP53 P04637 1/20 0.31
HPGD P15428 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5075116 0.88 SLC6A2 (0.32) SLC6A2TAAR1LMNACYP2D6
SCHEMBL5075153 0.88 SLC6A2 (0.35) SLC6A2TAAR1LMNACYP2D6TP53
SCHEMBL5080977 0.87 SLC6A2 (0.31) SLC6A2TAAR1
SCHEMBL5075143 0.87 SLC6A2 (0.31) SLC6A2TAAR1
SCHEMBL5075096 0.87 SLC6A2 (0.34) SLC6A2TAAR1LMNACYP2D6
SCHEMBL5078143 0.87 MAPT (0.31) SLC6A2TAAR1MAPT
SCHEMBL5081776 0.87 SLC6A2 (0.42) SLC6A2TAAR1LMNACYP2D6TP53
SCHEMBL5080914 0.87 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6
SCHEMBL5080964 0.85 DUT (0.32) SLC6A2TAAR1LMNACYP2D6
SCHEMBL5077395 0.85 ALDH1A1 (0.32) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed