SCHEMBL5075303

SCHEMBL5075303

CN(C)CCN(C)C.[Li]CCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 6/20 0.52
TSHR P16473 3/20 0.40
ALDH1A1 P00352 2/20 0.40
CA12 O43570 2/20 0.40
CA9 Q16790 2/20 0.40
CA2 P00918 1/20 0.40
CA3 P07451 1/20 0.40
CA4 P22748 1/20 0.40
CA6 P23280 1/20 0.40
CA5A P35218 1/20 0.40
CA7 P43166 1/20 0.40
CA14 Q9ULX7 1/20 0.40
CA5B Q9Y2D0 1/20 0.40
TDP1 Q9NUW8 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
CA1 P00915 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylaminoethanol SCHEMBL21407663 0.83 MAPT (0.55) DNM1TSHRALDH1A1LMNAMAPT
Hexane SCHEMBL16237730 0.81 DNM1 (0.75) DNM1TSHRALDH1A1CA12CA9
SCHEMBL9292699 0.80
SCHEMBL6369906 0.80 TSHR (0.50) DNM1TSHRALDH1A1TDP1LMNA
SCHEMBL811 0.80
SCHEMBL546944 0.78
SCHEMBL1617151 0.77
Phosphine SCHEMBL20135762 0.77
Barium SCHEMBL11668415 0.77
SCHEMBL3441314 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015035012-A1 FUSED THIOPHENE DITIN MONOMERS CORNING INCORPORATED (US) 2015-03-12 WO claimed
US-20150065722-A1 FUSED THIOPHENE DITIN MONOMERS CORNING INCORPORATED 2015-03-05 US claimed
CN-105073114-B Medicine for respiratory disorder 第三共株式会社 2017-07-28 CN disclosed
WO-2015035012-A1 FUSED THIOPHENE DITIN MONOMERS CORNING INCORPORATED (US) 2015-03-12 WO disclosed
US-20150065722-A1 FUSED THIOPHENE DITIN MONOMERS CORNING INCORPORATED 2015-03-05 US disclosed
CN-102950025-B Asymmetric hydrogenation catalyst of imine and its use SINOCHEM CORP 2014-09-10 CN disclosed
CN-102950025-A Asymmetric hydrogenation catalyst of imine and its use SINOCHEM CORP 2013-03-06 CN disclosed
EP-1885728-A1 CONVERSION OF AMORPHA-4,11- DIENE TO ARTEMISININ AND ARTEMISININ PRECURSORS Amyris Biotechnologies, Inc. (US) 2008-02-13 EP disclosed
US-7253232-B2 Thermoplastic compositions with enhanced melt flow and compatibility CIBA SPECIALTY CHEMICALS CORP. (US) 2007-08-07 US disclosed
WO-2006128126-A1 CONVERSION OF AMORPHA-4,11- DIENE TO ARTEMISININ AND ARTEMISININ PRECURSORS AMYRIS BIOTECHNOLOGIES, INC. (US) 2006-11-30 WO disclosed
US-20060270863-A1 CONVERSION OF AMORPHA-4,11-DIENE TO ARTEMISININ AND ARTEMISININ PRECURSORS AMYRIS BIOTECHNOLOGIES (US) 2006-11-30 US disclosed
US-5681975-A Single source metalloorgranic precursors to type 14-16 semiconductors RUTGERS, THE STATE UNIVERSITY (US) 1997-10-28 US disclosed
US-5283294-A Crystalline polymer in rubber elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1994-02-01 US disclosed
US-5220042-A Antiasthmatics, antiallergens, cardiovasculsr disorders OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-06-15 US disclosed
EP-0151995-B1 NOVEL 1,4-BENZOQUINONE DERIVATIVES AND BENZENE DERIVATIVES, AND PROCESS FOR PREPARING THE SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-12-23 EP disclosed
EP-0282241-B1 BETA-LACTAM COMPOUNDS AND PRODUCTION PROCESS THEREOF Tamura, Yasumitsu (JP) 1991-08-14 EP disclosed
EP-0336874-A1 Inverse phase polymerization THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-10-11 EP disclosed
EP-0151995-A2 Novel 1,4-benzoquinone derivatives and benzene derivatives, and process for preparing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1985-08-21 EP disclosed
US-4284581-A LITHIUM 1,1'-BINAPHTHYL-2,2'-DIOXYALUMINUM HYDRIDE, REDUCING AGENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1981-08-18 US disclosed
US-4029718-A MOLDING MATERIALS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060270863-A1 CONVERSION OF AMORPHA-4,11-DIENE TO ARTEMISININ AND ARTEMISININ PRECURSORS SQLE, CYP4A11, DHPS DNM1 1359/4885TSHR 4597/4885ALDH1A1 217/4885
US-20150065722-A1 FUSED THIOPHENE DITIN MONOMERS TTL, THEM6, ITK DNM1 2909/4885TSHR 1590/4885ALDH1A1 2618/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.