Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PGD | P52209 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282741 | 0.73 | SLC22A6 (0.43) | SLC22A6TDP1PGDSMN1; SMN2 | |
| SCHEMBL3282078 | 0.73 | LMNA (0.34) | MEN1KMT2ATSHRMMP1MMP2 | |
| SCHEMBL26324855 | 0.71 | TSHR (0.43) | MEN1KMT2ATSHRTDP1SMN1; SMN2 | |
| SCHEMBL14558024 | 0.69 | TDP1 (0.42) | SLC22A6TSHRTDP1PGDSMN1; SMN2 | |
| SCHEMBL8106901 | 0.68 | RNPEP (0.34) | MEN1KMT2ATSHRMMP1MMP2 | |
| SCHEMBL1941442 | 0.66 | TDP1 (0.43) | SLC22A6TSHRTDP1PGDSMN1; SMN2 | |
| SCHEMBL1941444 | 0.66 | TDP1 (0.43) | SLC22A6TSHRTDP1PGDSMN1; SMN2 | |
| SCHEMBL28117913 | 0.66 | TDP1 (0.43) | SLC22A6TSHRTDP1PGDSMN1; SMN2 | |
| SCHEMBL8853350 | 0.66 | TDP1 (0.43) | SLC22A6TSHRTDP1PGDSMN1; SMN2 | |
| SCHEMBL20131344 | 0.66 | TDP1 (0.39) | SLC22A6TDP1PGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937246-A2 | HYDROXY-OLIGOCARBOXYLIC ESTERS: EFFECTS ON NERVE AND USE FOR CUTANEOUS AND MUCOCUTANEOUS ORGANS OR SITES | Yu, Ruey J., Dr. (US) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007047486-A2 | HYDROXY-OLIGOCARBOXYLIC ESTERS: EFFECTS ON NERVE AND USE FOR CUTANEOUS AND MUCOCUTANEOUS ORGANS OR SITES | YU RUEY J (US) | 2007-04-26 | — | — | WO | disclosed |