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Sugi Predict / Compounds / SCHEMBL6025501

SCHEMBL6025501

SCHEMBL6025501

C=CC(=O)N1C(C)(C)CC(C(c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)(C2CC(C)(C)N(C(=O)C=C)C(C)(C)C2)C(Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)(C(=O)O)C(=O)O)CC1(C)C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.37
▸ MAPT P10636 4/20 0.37
▸ MEN1 O00255 3/20 0.37
▸ KMT2A Q03164 3/20 0.37
▸ CYP1A2 P05177 2/20 0.37
▸ CYP3A4 P08684 2/20 0.37
▸ TSHR P16473 2/20 0.37
▸ MAPK1 P28482 2/20 0.37
▸ BLM P54132 2/20 0.37
▸ ATM Q13315 2/20 0.37
▸ HIF1A Q16665 2/20 0.37
▸ NPSR1 Q6W5P4 2/20 0.37
▸ USP2 O75604 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ GAA P10253 5/20 0.36
▸ ALOX15 P16050 2/20 0.33
▸ GMNN O75496 1/20 0.33
▸ GABBR2 O75899 1/20 0.33
▸ LMNA P02545 1/20 0.33
▸ TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10904372 0.82 MAOB (0.33) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL5075835 0.81 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL9866030 0.79 ALDH1A1 (0.39) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL9865425 0.77 GAA (0.38) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL15023981 0.76 ALDH1A1 (0.35) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL3425141 0.76 ALDH1A1 (0.40) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL15329996 0.75 GAA (0.40) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL10487560 0.75 GAA (0.38) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL11290983 0.74 ALDH1A1 (0.36) ALDH1A1MAPTMEN1KMT2ACYP1A2
SCHEMBL11085415 0.73 ALDH1A1 (0.38) ALDH1A1MAPTMEN1KMT2ACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6437164-B1 REACTING BIPHENYL AND PHOSPHORUS TRICHLORIDE IN PRESENCE OF ALUMINUM CHLORIDE, ADDING PYRIDINE, RESULTING DICHLOROPHOSPHINE IS REACTED WITH A PHENOL, REMOVING FORMED PYRIDINE-ALUMINUM CHLORIDE COMPLEX YOSHITOMI FINE CHEMICALS, LTD. (JP) 2002-08-20 — — US claimed
EP-1463774-B1 NAPHTHYLTRIAZINES AS STABILIZERS FOR ORGANIC MATERIAL BASF SE (DE) 2013-07-31 — — EP disclosed
EP-2570259-A1 FLAME-RETARDANT POLYMER MEMBER, FLAME-RETARDANT PRODUCT, AND FLAME-RETARDING METHOD Nitto Denko Corporation (JP) 2013-03-20 — — EP disclosed
US-20130040131-A1 FLAME-RETARDANT POLYMER MEMBER, FLAME-RETARDANT ARTICLE, AND FLAME-RETARDING METHOD NITTO DENKO CORPORATION (JP) 2013-02-14 — — US disclosed
US-20130035427-A1 THERMOPLASTIC POLYMER COMPOSITION AND PROCESSING STABILISER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-02-07 — — US disclosed
US-20060287416-A1 Water based concetrated product forms of light stabilizers made by a heterophase polymerization technique CIBA SPECIALTY CHEMICALS CORP. 2006-12-21 — — US disclosed
US-7087753-B2 Naphthyltriazines as stabilizers for organic material CIBA SPECIALTY CHEMICALS CORP. (US) 2006-08-08 — — US disclosed
US-20050169859-A1 Naphthyltriazines as stabilizers for organic material TOAN VIEN V (CH) 2005-08-04 — — US disclosed
US-20050038245-A1 Naphthyltriazines as stabilizers for organic material CIBA SPECIALTY CHEMICALS CORP. 2005-02-17 — — US disclosed
EP-1463774-A1 NAPHTHYLTRIAZINES AS STABILIZERS FOR ORGANIC MATERIAL Ciba SC Holding AG (CH) 2004-10-06 — — EP disclosed
US-5703150-A STABILIZERS; HEAT, OXIDATION RESISTANCE YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) 1997-12-30 — — US disclosed
EP-0520938-B1 UV-absorber containing photographic material CIBA GEIGY AG (CH) 1997-09-24 — — EP disclosed
EP-0531258-B1 Photographic material containing a UV-absorber CIBA GEIGY AG (CH) 1997-09-10 — — EP disclosed
US-5488108-A PROTECTIVE COATINGS FOR RADIATION RESISTANCE CIBA-GEIGY CORPORATION (US) 1996-01-30 — — US disclosed
US-5410048-A Protecting photographic materials from actinic light CIBA-GEIGY CORPORATION (US) 1995-04-25 — — US disclosed
US-5300414-A Tris(2-hydroxyphenyl)-s-triazines CIBA-GEIGY CORPORATION (US) 1994-04-05 — — US disclosed
EP-0531258-A1 Photographic material containing a UV-absorber CIBA-GEIGY AG (CH) 1993-03-10 — — EP disclosed
EP-0530135-A1 UV-absorber containing photographic material CIBA-GEIGY AG (CH) 1993-03-03 — — EP disclosed
EP-0520938-A1 UV-absorber containing photographic material CIBA-GEIGY AG (CH) 1992-12-30 — — EP disclosed
US-4897438-A BLEND WITH A PHENOLIC RESIN HITACHI CHEMICAL COMPANY, LTD. (JP) 1990-01-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038245-A1 Naphthyltriazines as stabilizers for organic material POT1, TYR, H1-2 ALDH1A1 375/4885MAPT 600/4885MEN1 1969/4885
US-20050169859-A1 Naphthyltriazines as stabilizers for organic material POT1, H1-2, TYR ALDH1A1 275/4885MAPT 816/4885MEN1 1828/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.