Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | AHCY | P23526 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ADA | P00813 | 4/20 | 0.46 |
| ▸ | PDE2A | O00408 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL985389 | 0.82 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BALDH1A1AHCY | |
| SCHEMBL5077097 | 0.82 | ADORA2A (0.51) | ADORA2AADORA1ADORA2BALDH1A1FGFR1 | |
| SCHEMBL12922453 | 0.79 | ADORA2A (0.67) | ADORA2AADORA1ADORA2BALDH1A1AHCY | |
| SCHEMBL12948656 | 0.79 | ADORA2A (0.59) | ADORA2AADORA1ADORA2BALDH1A1AHCY | |
| SCHEMBL5965418 | 0.76 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BALDH1A1AHCY | |
| SCHEMBL987631 | 0.76 | ADORA2A (0.74) | ADORA2AADORA1ADORA2BALDH1A1AHCY | |
| SCHEMBL8219215 | 0.75 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BALDH1A1FGFR1 | |
| SCHEMBL8215843 | 0.75 | ADORA2A (0.62) | ADORA2AADORA1ADORA2BALDH1A1FGFR1 | |
| SCHEMBL1074972 | 0.75 | ADORA2A (1.00) | ADORA2AADORA1ADORA2BALDH1A1AHCY | |
| SCHEMBL11487766 | 0.75 | ADORA2A (0.71) | ADORA2AADORA1ADORA2BALDH1A1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080171049-A1 | Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof | NINGBO ZIYUAN PHARMACEUTICALS, INC. (CN) | 2008-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171049-A1 | Reversible inhibitors of S-adenosyl-L-homocysteine hydrolase and uses thereof | AHCY, AHCYL1, BHMT | ADORA2A 72/4885ADORA1 77/4885ADORA2B 183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.