Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RXRA | P19793 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11291883 | 0.83 | LMNA (0.54) | LMNASMN1; SMN2CYP1A2KDM4EAGTR1 | |
| SCHEMBL23973559 | 0.83 | KDM4E (0.60) | LMNASMN1; SMN2CYP1A2KDM4EKMT2A | |
| SCHEMBL28430550 | 0.81 | LMNA (0.59) | LMNASMN1; SMN2CYP1A2KDM4EAGTR1 | |
| SCHEMBL28439054 | 0.81 | LMNA (0.59) | LMNASMN1; SMN2CYP1A2KDM4EAGTR1 | |
| SCHEMBL28430552 | 0.81 | LMNA (0.59) | LMNASMN1; SMN2CYP1A2KDM4EAGTR1 | |
| SCHEMBL10813524 | 0.81 | GAA (0.50) | LMNASMN1; SMN2ATMMAPTL3MBTL1 | |
| SCHEMBL29941729 | 0.80 | LMNA (0.82) | LMNASMN1; SMN2CYP1A2KDM4EAGTR1 | |
| SCHEMBL2328960 | 0.80 | LMNA (0.82) | LMNASMN1; SMN2CYP1A2KDM4EAGTR1 | |
| SCHEMBL10801283 | 0.79 | ADRB2 (0.55) | LMNASMN1; SMN2CYP1A2KDM4EKMT2A | |
| Guaifenesin SCHEMBL28062894 | 0.79 | CYP1A2 (0.84) | LMNASMN1; SMN2CYP1A2KDM4EAGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190391092-A1 | METABOLIC PROFILING WITH MAGNETIC RESONANCE MASS SPECTROMETRY (MRMS) | Oregon Institute of Science and Medicine | 2019-12-26 | — | — | US | disclosed |
| US-20080014261-A1 | Non-narcotic biphasic release compositions and methods for treatment of coughing, sneezing, rhinorrhea, and/or nasal obstruction | EVERETT LABORATORIES, INC. | 2008-01-17 | — | — | US | disclosed |
| US-20080008772-A1 | Narcotic biphasic release compositions and methods for treatment of coughing, sneezing, rhinorrhea, and/or nasal obstruction | EVERETT LABORATORIES, INC. | 2008-01-10 | — | — | US | disclosed |