SCHEMBL5076208

SCHEMBL5076208

COC(OC)[SiH2]CCc1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
HPGD P15428 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
CASP1 P29466 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TAAR1 Q96RJ0 3/20 0.38
ATM Q13315 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
CYP2A6 P11509 1/20 0.37
HTR2A P28223 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
LOXL2 Q9Y4K0 1/20 0.37
RECQL P46063 1/20 0.36
IDO1 P14902 1/20 0.35
AOC3 Q16853 1/20 0.35
LTA4H P09960 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL163506 0.90 TAAR1 (0.34) TAAR1SMN1; SMN2AOC3
SCHEMBL31070320 0.89 IDO1 (0.41) IDO1AOC3
SCHEMBL2246130 0.86 TAAR1 (0.38) TAAR1AOC3
SCHEMBL17075374 0.81 L3MBTL1 (0.37) ALDH1A1HPGDALOX15ALOX12CASP1
SCHEMBL8961186 0.81 LOXL2 (0.38) TAAR1LOXL2
SCHEMBL10612702 0.79 MAOB (0.49) ALDH1A1CASP1TAAR1SMN1; SMN2RECQL
SCHEMBL15329315 0.76 TAAR1 (0.46) ALOX12TAAR1
SCHEMBL2242171 0.74 CASR (0.31) TAAR1
SCHEMBL10612696 0.74 ALDH1A1 (0.34) ALDH1A1HPGDALOX15CASP1HSD17B10
SCHEMBL10356064 0.73 CA1 (0.38) ALDH1A1HPGDALOX15ALOX12CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559632-B2 Weather-resistant, fungal-resistant, and stain-resistant coatings and methods of applying on wood, masonry, or other porous materials UNIVERSITY OF HOUSTON SYSTEM (US) 2026-02-24 US disclosed
US-12312534-B2 Treating fluid comprising hydrocarbons, water, and polymer CHEVRON U.S.A. INC. (US) 2025-05-27 US disclosed
US-12215276-B2 Ph control in fluid treatment CHEVRON U.S.A. INC. (US) 2025-02-04 US disclosed
US-20240067865-A1 TREATING FLUID COMPRISING HYDROCARBONS, WATER, AND POLYMER CHEVRON U.S.A. INC. 2024-02-29 US disclosed
US-11834606-B2 Treating fluid comprising hydrocarbons, water, and polymer CHEVRON U.S.A. INC. (US) 2023-12-05 US disclosed
US-20230323193-A1 PH CONTROL IN FLUID TREATMENT CHEVRON U.S.A. INC. 2023-10-12 US disclosed
US-11591893-B2 PH control in fluid treatment CHEVRON U.S.A. INC. (US) 2023-02-28 US disclosed
US-20220259442-A1 Weather-Resistant, Fungal-Resistant, And Stain-Resistant Coatings And Methods Of Applying On Wood, Masonry, Or Other Porous Materials UNIVERSITY OF HOUSTON SYSTEM (US) 2022-08-18 US disclosed
US-11345821-B2 Weather-resistant, fungal-resistant, and stain-resistant coatings and methods of applying on wood, masonry, or other porous materials UNIVERSITY OF HOUSTON SYSTEM (US) 2022-05-31 US disclosed
US-20220145157-A1 TREATING FLUID COMPRISING HYDROCARBONS, WATER, AND POLYMER CHEVRON U.S.A. INC. 2022-05-12 US disclosed
EP-3218438-A1 WEATHER-RESISTANT, FUNGAL-RESISTANT, AND STAIN-RESISTANT COATINGS AND METHODS OF APPLYING ON WOOD, MASONRY, OR OTHER POROUS MATERIALS The University Of Houston System (US) 2017-09-20 EP disclosed
CN-107109777-A Antifouling, anti-coloring pollution the method applied without fluorine coating and on material 休斯敦大学系统 2017-08-29 CN disclosed
WO-2017031289-A1 PESTICIDE RETENTION COATING COMPOSITIONS AND USES THEREOF INTEGRICOTE, INC. (US) 2017-02-23 WO disclosed
WO-2016077573-A1 WEATHER-RESISTANT, FUNGAL-RESISTANT, AND STAIN-RESISTANT COATINGS AND METHODS OF APPLYING ON WOOD, MASONRY, OR OTHER POROUS MATERIALS UNIVERSITY OF HOUSTON SYSTEM (US) 2016-05-19 WO disclosed
CN-1802394-B Polyorganosiloxane-containing graft copolymer, resin composition containing the same, and method for producing polyorganosiloxane emulsion KANEGAFUCHI CHEMICAL IND 2012-05-09 CN disclosed
EP-1887019-A1 POLYORGANOSILOXANE-CONTAINING GRAFT COPOLYMER AND VINYL CHLORIDE RESIN COMPOSITIONS CONTAINING THE COPOLYMER Kaneka Corporation (JP) 2008-02-13 EP disclosed
CN-1950411-A Graft copolymer and resin compositions containing the same KANEGAFUCHI CHEMICAL IND (JP) 2007-04-18 CN disclosed
CN-1802394-A Polyorganosiloxane-containing graft copolymer, resin composition containing the same, and method for producing polyorganosiloxane emulsion KANEGAFUCHI CHEMICAL IND (JP) 2006-07-12 CN disclosed
CN-1802414-A Rubber-modified styrene resin composition KANEGAFUCHI CHEMICAL IND (JP) 2006-07-12 CN disclosed
CN-1768113-A Polyester resin composition KANEGAFUCHI CHEMICAL IND (JP) 2006-05-03 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12559632-B2 Weather-resistant, fungal-resistant, and stain-resistant coatings and methods of applying on wood, masonry, or other porous materials GMDS, MGAM, STS ALDH1A1 4200/4885HPGD 3234/4885ALOX15 3868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.