SCHEMBL8725980

SCHEMBL8725980

CC1(C(=O)Nc2ccccc2)C2C=CC(C2)C1C(=O)O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.52
POLB P06746 4/20 0.52
ALDH1A1 P00352 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CTDSP1 Q9GZU7 2/20 0.52
LMNA P02545 5/20 0.49
KDM4E B2RXH2 2/20 0.49
P2RX7 Q99572 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2C9 P11712 1/20 0.40
TSHR P16473 1/20 0.40
CYP2C19 P33261 1/20 0.40
EPHX2 P34913 1/20 0.38
NAPRT Q6XQN6 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SLC6A2 P23975 1/20 0.37
MC4R P32245 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17652072 0.77 TDP1 (0.56) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL1062711 0.77 TDP1 (0.56) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL5076356 0.77 TDP1 (0.56) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL20346213 0.76 TDP1 (0.45) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL10949610 0.75 TDP1 (0.45) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL23080652 0.74 NAPRT (0.48) POLBALDH1A1MEN1KMT2ALMNA
SCHEMBL4608055 0.73 TDP1 (0.43) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL8731646 0.72 TDP1 (0.42) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL11570246 0.71 ALDH1A1 (0.43) TDP1POLBALDH1A1MEN1KMT2A
SCHEMBL8996568 0.70 TDP1 (0.41) TDP1POLBALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10329383-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2019-06-25 US disclosed
US-20190112406-A1 Resins and Radomes Including Them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2019-04-18 US disclosed
US-20180258223-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2018-09-13 US disclosed
WO-2018151800-A2 RADOME FABRICATION USING CYCLIC OLEFIN RESIN IN LIQUID MOLDING SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-08-23 WO disclosed
US-9914803-B2 Cyanate resin blends and radomes including them SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION (US) 2018-03-13 US disclosed
EP-3013882-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM Saint-gobain Performance Plastics Corporation (US) 2016-05-04 EP disclosed
EP-3013869-A1 RESINS AND RADOMES INCLUDING THEM Saint-gobain Performance Plastics Corporation (US) 2016-05-04 EP disclosed
CN-105339407-A Cyanate resin blends and radomes including them SAINT GOBAIN PERFORMANCE PLAST 2016-02-17 CN disclosed
US-20150004423-A1 RESINS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2015-01-01 US disclosed
US-20150002364-A1 CYANATE RESIN BLENDS AND RADOMES INCLUDING THEM SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION 2015-01-01 US disclosed
EP-0544304-B1 Catalyst composition for hydrogenating olefinically unsaturated polymers JAPAN SYNTHETIC RUBBER CO LTD (JP) 1998-02-04 EP disclosed
EP-0434469-B1 Hydrogenation catalyst composition and process for hydrogenating olefinically unsaturated polymer using the same JAPAN SYNTHETIC RUBBER CO LTD (JP) 1995-02-22 EP disclosed
US-5270274-A Catalyst composition for hydrogenating olefinically unsaturated polymers JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-12-14 US disclosed
EP-0544304-A1 Catalyst composition for hydrogenating olefinically unsaturated polymers JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1993-06-02 EP disclosed
US-5169905-A Using a bis(cyclopentadienyl)transition metal compound and an alkali aluminum organic complex as catalyst JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-08 US disclosed
EP-0339986-B1 NOVEL CATALYST FOR HYDROGENATION OF POLYMER AND PROCESS FOR HYDROGENATING POLYMER WITH THE CATALYST JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1992-12-02 EP disclosed
EP-0434469-A2 Hydrogenation catalyst composition and process for hydrogenating olefinically unsaturated polymer using the same JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1991-06-26 EP disclosed
US-4250063-A COORDINATION CATALYST COMPRISING AN ORGANIC COMPLEX OF TUNGSTEN OR MOLYBDENUM, A TITANIUM TETRAHALIDE, AND AN N-HALO IMIDE, A SULFIDE, A SULFOXIDE, OR A PHOSPHINE; POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1981-02-10 US disclosed
US-4106943-A RING-OPENED POLYMER OR COPOLYMER OF NORBORNENE DERIVATIVE JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1978-08-15 US disclosed
US-4011386-A RING OPENING, POLYALKENAMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JA) 1977-03-08 US disclosed