Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 2/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.37 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | TDO2 | P48775 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL222542 | 1.00 | ACP3 (0.47) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL197100 | 0.92 | ACP3 (0.48) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL9132059 | 0.90 | ACP3 (0.44) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL1398395 | 0.90 | ACP3 (0.47) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL7165416 | 0.90 | ACP3 (0.47) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL7769635 | 0.90 | ACP3 (0.47) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| Bromide SCHEMBL5510650 | 0.88 | ACP3 (0.46) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL15412907 | 0.88 | ACP3 (0.46) | ACP3KCNH2SIGMAR1SLC6A4SLC6A2 | |
| SCHEMBL197085 | 0.80 | KCNH2 (0.50) | KCNH2SIGMAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL15288212 | 0.78 | SIGMAR1 (0.49) | KCNH2SIGMAR1CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7048292-A | — | — | None | — | — | JP | disclosed |
| EP-1572606-A4 | CROSS-COUPLING SYNTHESIS OF ALKYL (DIALKYLPHENYL) INDENES | BOULDER SCIENT CO (US) | 2008-07-09 | — | — | EP | disclosed |
| US-7205427-B2 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | BOULDER SCIENTIFIC COMPANY (US) | 2007-04-17 | — | — | US | disclosed |
| EP-1572606-A2 | CROSS-COUPLING SYNTHESIS OF ALKYL (DIALKYLPHENYL) INDENES | BOULDER SCIENTIFIC COMPANY (US) | 2005-09-14 | — | — | EP | disclosed |
| US-20040267072-A1 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | ANTARES CAPITAL LP, AS AGENT | 2004-12-30 | — | — | US | disclosed |
| WO-2003101601-A2 | CROSS-COUPLING SYNTHESIS OF ALKYL (DIALKYLPHENYL) INDENES | BOULDER SCIENTIFIC COMPANY (US) | 2003-12-11 | — | — | WO | disclosed |
| EP-0637580-B1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 2002-08-14 | — | — | EP | disclosed |
| US-6063940-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-05-16 | — | — | US | disclosed |
| US-5637736-A | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-10 | — | — | US | disclosed |
| EP-0535635-B1 | Tolane derivative, liquid crystal composition containing the derivative, and liquid crystal display device using the composition | SEIKO EPSON CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5437815-A | Blending with ordinary liquid crystal compounds broadens practical temperature range of composition and produces an enlarged double refraction anisotropy | SEIKO EPSON CORPORATION (JP) | 1995-08-01 | — | — | US | disclosed |
| JP-H0748292-A | PRODUCTION OF 4-PHENYL-1-BUTENE | SUMITOMO CHEM CO LTD | 1995-02-21 | — | — | JP | disclosed |
| EP-0637580-A1 | Process for preparing 1-bromoalkylbenzene derivatives and intermediates thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1995-02-08 | — | — | EP | disclosed |
| US-5314976-A | Heterocyclic polymers | NATIONAL SCIENCE COUNCIL (TW) | 1994-05-24 | — | — | US | disclosed |
| US-5272234-A | Photo-responsive conductive polymers and the processes of making the same | NATIONAL SCIENCE COUNCIL (TW) | 1993-12-21 | — | — | US | disclosed |
| EP-0535635-A1 | Tolane derivative, liquid crystal composition containing the derivative, and liquid crystal display device using the composition | SEIKO EPSON CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040267072-A1 | Cross-coupling synthesis of alkyl (dialkylphenyl) indenes | DDT, DUOX2, DYRK4 | ACP3 2364/4885KCNH2 682/4885SIGMAR1 4528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.