Fluorene

Fluorene

SCHEMBL5076892

Nc1ccccc1.Nc1ccccc1.c1ccc2c(c1)Cc1ccccc1-2

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.65
NPC1 O15118 1/20 0.65
ALDH1A1 P00352 1/20 0.65
LMNA P02545 1/20 0.65
MAPT P10636 1/20 0.65
HPGD P15428 1/20 0.65
RAB9A P51151 1/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
TSHR P16473 2/20 0.55
MAOA P21397 1/20 0.52
SRD5A2 P31213 1/20 0.47
PNMT P11086 1/20 0.44
BCHE P06276 2/20 0.43
ADORA1 P30542 2/20 0.43
ADORA2A P29274 1/20 0.43
CES1 P23141 1/20 0.43
ACHE P22303 2/20 0.42
DAPK3 O43293 2/20 0.41
LTK P29376 2/20 0.41
MAPK8 P45983 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL6009482 1.00 KDM4E (0.65) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL14118022 0.87 MAOA (0.65) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL28818074 0.84 MAOA (0.62) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL545861 0.84 MAOA (0.68) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL29355380 0.84 MAOA (0.68) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL29478468 0.84 MAOA (0.68) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL8180 0.84 MAOA (0.68) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL31388525 0.84 MAOA (0.68) KDM4ENPC1ALDH1A1LMNAMAPT
Fluorene SCHEMBL1039293 0.81 MAOA (0.65) KDM4ENPC1ALDH1A1LMNAMAPT
SCHEMBL6481957 0.81 MAOA (0.65) KDM4ENPC1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113150545-B Polymer film containing nano fullerene and preparation method thereof 北京市科学技术研究院分析测试研究所(北京市理化分析测试中心) 2022-11-15 CN claimed
US-20080124534-A1 Polyamide, Film, and Image Display Device FUJIFILM CORPORATION (JP) 2008-05-29 US disclosed
WO-2006030873-A1 POLYAMIDE, FILM, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-03-23 WO disclosed
EP-0231506-B1 SOLUBLE HEAT-RESISTANT AROMATIC POLYAMIDE NIPPON STEEL CORPORATION (JP) 1991-03-20 EP disclosed