SCHEMBL6481957

SCHEMBL6481957

c1ccc2c(c1)Cc1ccccc1-c1ccccc1-2

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 3/20 0.65
▸ KDM4E B2RXH2 2/20 0.58
▸ NPC1 O15118 2/20 0.58
▸ MAPT P10636 2/20 0.58
▸ RAB9A P51151 2/20 0.58
▸ SMN1; SMN2 Q16637 2/20 0.58
▸ ALDH1A1 P00352 1/20 0.58
▸ LMNA P02545 1/20 0.58
▸ HPGD P15428 1/20 0.58
▸ CES1 P23141 2/20 0.52
▸ BCHE P06276 1/20 0.52
▸ SRD5A2 P31213 1/20 0.50
▸ PLK4 O00444 1/20 0.48
▸ DAPK3 O43293 1/20 0.48
▸ PIM1 P11309 1/20 0.48
▸ PDGFRA P16234 1/20 0.48
▸ LTK P29376 1/20 0.48
▸ MAP2K2 P36507 1/20 0.48
▸ FLT3 P36888 1/20 0.48
▸ MAPK8 P45983 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluorene SCHEMBL17107853 1.00 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL19516585 1.00 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29355380 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL545861 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL31388525 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL8180 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL29478468 0.97 MAOA (0.68) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL6739194 0.93 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL9791437 0.93 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A
Fluorene SCHEMBL19610620 0.93 MAOA (0.65) MAOAKDM4ENPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3243812-B1 POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2025-07-16 — — EP disclosed
EP-4495093-A2 POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2025-01-22 — — EP disclosed
US-10593885-B2 Polycyclic compound and organic electroluminescence device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-03-17 — — US disclosed
EP-3243812-A2 POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2017-11-15 — — EP disclosed
US-20170324037-A1 POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2017-11-09 — — US disclosed
US-20050096491-A1 Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2005-05-05 — — US disclosed
US-20040115475-A1 Aromatic methylidene compound, methylstyrul compound for producing the same, production electroluminescent element MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-06-17 — — US disclosed
US-20030224206-A1 Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. 2003-12-04 — — US disclosed
EP-1355921-A2 MODULATORS OF CELLULAR PROLIFERATION AND ANGIOGENESIS, METHODS FOR USE AND IDENTIFICATION THEREOF North Shore-Long Island Jewish Health System (US) 2003-10-29 — — EP disclosed
WO-2002002593-A2 MODULATORS OF CELLULAR PROLIFERATION AND ANGIOGENESIS, METHODS FOR USE AND IDENTIFICATION THEREOF NORTH SHORE-LONG ISLAND JEWISH HEALTH SYSTEM (US) 2002-01-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10593885-B2 Polycyclic compound and organic electroluminescence device including the same ARL1, AR, RIF1 MAOA 2550/4885KDM4E 2787/4885NPC1 2349/4885
US-20170324037-A1 POLYCYCLIC COMPOUND AND ORGANIC ELETROLUMINESCENCE DEVICE INCLUDING THE SAME AR, ARL1, ESR2 MAOA 2276/4885KDM4E 3639/4885NPC1 2099/4885
US-20050096491-A1 Aromatic methylidene compound, methylstyryl compound for producing the same, production method therefor, and organic electroluminescent element OR51E2, CYP4F11, ACAD11 MAOA 1346/4885KDM4E 909/4885NPC1 1470/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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