Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5623178 | 0.95 | TSHR (0.43) | TSHRALDH1A1TDP1DNM1TRPM8 | |
| SCHEMBL27477168 | 0.91 | TSHR (0.50) | TSHRALDH1A1TDP1DNM1TRPM8 | |
| SCHEMBL9324912 | 0.91 | TSHR (0.50) | TSHRALDH1A1TDP1DNM1TRPM8 | |
| SCHEMBL29055263 | 0.88 | TSHR (0.62) | TSHRALDH1A1TDP1DNM1TRPM8 | |
| SCHEMBL230466 | 0.87 | DNM1 (0.37) | TSHRDNM1TRPM8OPRM1 | |
| SCHEMBL28996019 | 0.84 | TSHR (0.62) | TSHRALDH1A1TDP1DNM1OPRM1 | |
| SCHEMBL28996073 | 0.84 | TSHR (0.62) | TSHRALDH1A1TDP1DNM1OPRM1 | |
| SCHEMBL21462890 | 0.82 | TSHR (0.59) | TSHRALDH1A1TDP1DNM1OPRM1 | |
| SCHEMBL29055258 | 0.82 | OPRM1 (0.41) | TSHRALDH1A1DNM1TRPM8OPRM1 | |
| SCHEMBL28993072 | 0.76 | TSHR (0.62) | TSHRALDH1A1TDP1DNM1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107699131-A | A kind of waterproof powdery paints and preparation method thereof | 浙江华彩新材料有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-107641468-A | A kind of water proof fire retardant powdery paints and preparation method thereof | 浙江华彩新材料有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-104211654-B | A kind of preparation method and intermediate of Rivaroxaban intermediate | 联化科技（台州）有限公司 | 2017-03-29 | — | — | CN | claimed |
| CN-106146457-A | A kind of 5-chloro-2-acyl chlorides thiophene intermediate and preparation method thereof | 联化科技（台州）有限公司 | 2016-11-23 | — | — | CN | claimed |
| CN-104211654-A | Preparation method of rivaroxaban intermediate and intermediate | LIANHUA SCIENCE & TECHNOLOGY TAIZHOU CO LTD | 2014-12-17 | — | — | CN | claimed |
| US-20050001333-A1 | Method for producing, via organometallic compounds, organic intermediate products | ARCHIMICA GMBH (DE) | 2005-01-06 | — | — | US | claimed |
| US-6013847-A | USING PLATINUM CONTAINING CATALYST IN THE PRESENCE OF WATER AND AN ORGANIC CHLORIDE; ALLEVIATING THE DEACTIVATION OF THE CATALYST CAUSED BY THE PRESENCE OF WATER BY HAVING AT LEAST ONE ORGANIC CHLORINE COMPOUND PRESENT IN THE REACTION MIXTURE | PHILLIPS PETROLEUM COMPANY (US) | 2000-01-11 | — | — | US | claimed |
| US-5557029-A | ADDITION OF HCL OR ORGANIC CHLORIDE TO PREVENT DEACTIVATION OF CATALYST BY SULFUR IMPURITIES | PHILLIPS PETROLEUM COMPANY (US) | 1996-09-17 | — | — | US | claimed |
| US-4046819-A | Alkylation of alkyl, cycloalkyl and aralkyl halides | UOP INC. (US) | 1977-09-06 | — | — | US | claimed |
| CN-107923060-B | Aqueous copper plating bath and method for depositing copper or copper alloy onto a substrate | 埃托特克德国有限公司 | 2020-03-10 | — | — | CN | disclosed |
| CN-107674095-B | A kind of vitamin D3Cyclic phosphate and preparation method thereof | 无锡福祈制药有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-107674097-B | A kind of vitamin D3Cyclophosphamide and preparation method thereof | 无锡福祈制药有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-105384608-B | A kind of cumene amphyl and preparation method thereof | 四川海思科制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-105384607-B | A kind of cumene amphyl and preparation method thereof | 四川海思科制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| WO-1994012858-A1 | SOLID STATE DEVICE FOR MONITORING INTEGRAL VALUES OF TIME AND TEMPERATURE OF STORAGE OF PERISHABLES | JP LABORATORIES, INC. (US) | 1994-06-09 | — | — | WO | disclosed |
| US-5254473-A | Solid state device for monitoring integral values of time and temperature of storage of perishables | JP LABORATORIES | 1993-10-19 | — | — | US | disclosed |
| EP-0398889-A4 | DEGRADATION OF ORGANOCHLORINES | — | 1991-07-31 | — | — | EP | disclosed |
| EP-0398889-A1 | DEGRADATION OF ORGANOCHLORINES | THE UNIVERSITY OF SYDNEY (AU) | 1990-11-28 | — | — | EP | disclosed |
| WO-1989005172-A1 | DEGRADATION OF ORGANOCHLORINES | THE UNIVERSITY OF SYDNEY (AU) | 1989-06-15 | — | — | WO | disclosed |
| US-4046819-A | Alkylation of alkyl, cycloalkyl and aralkyl halides | UOP INC. (US) | 1977-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050001333-A1 | Method for producing, via organometallic compounds, organic intermediate products | NISCH, HDHD5, TYR | TSHR 140/4885ALDH1A1 1849/4885TDP1 4482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.