SCHEMBL5077102

SCHEMBL5077102

C/C=C(/C(=O)O)c1ccccc1COc1cc(Cl)c(OCc2ccc(Cl)cc2)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.48
MRGPRX4 Q96LA9 3/20 0.44
NR4A2 P43354 2/20 0.43
MAOB P27338 5/20 0.42
MAOA P21397 4/20 0.42
MAPT P10636 1/20 0.41
FFAR1 O14842 1/20 0.40
FFAR4 Q5NUL3 1/20 0.40
LMNA P02545 1/20 0.39
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
FABP5 Q01469 1/20 0.39
TP53 P04637 1/20 0.39
HTT P42858 1/20 0.39
ALDH1A1 P00352 1/20 0.39
S1PR1 P21453 1/20 0.39
PRKX P51817 1/20 0.39
ACVR1 Q04771 1/20 0.39
S1PR5 Q9H228 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151247 0.95 HIF1A (0.44) HIF1AMRGPRX4NR4A2MAOBLMNA
SCHEMBL5075956 0.91 HIF1A (0.48) HIF1AMRGPRX4NR4A2MAOBMAOA
SCHEMBL5075957 0.91 HIF1A (0.48) HIF1AMRGPRX4NR4A2MAOBMAOA
SCHEMBL5075922 0.89 FABP3 (0.52) MRGPRX4NR4A2MAPTFFAR1FABP3
SCHEMBL5075977 0.87 RAB9A (0.48) MRGPRX4NR4A2MAOBMAOAMAPT
SCHEMBL5079483 0.85 MRGPRX4 (0.46) HIF1AMRGPRX4NR4A2MAOBMAOA
SCHEMBL6151249 0.85 HIF1A (0.44) HIF1AMRGPRX4MAOBLMNATP53
SCHEMBL6151245 0.85 HIF1A (0.44) HIF1AMRGPRX4MAOBLMNATP53
SCHEMBL5080507 0.85 TP53 (0.41) HIF1AMRGPRX4NR4A2MAOBMAOA
SCHEMBL5076979 0.84 TP53 (0.40) HIF1AMRGPRX4NR4A2MAOBMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US claimed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US claimed
US-7435844-B2 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2008-10-14 US disclosed
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides ISAGRO RICERCA S.R.L. (IT) 2006-10-19 US disclosed
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060235075-A1 Analogous compounds of strobilurines and their use as acaricides and insecticides DDT, RYR1, TPMT HIF1A 4554/4885MRGPRX4 989/4885NR4A2 1863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.