SCHEMBL5077173

SCHEMBL5077173

COCC(CO[Si](C)(C)C)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.37
TAAR1 Q96RJ0 1/20 0.37
LMNA P02545 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TRPA1 O75762 1/20 0.32
LTA4H P09960 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
TP53 P04637 1/20 0.30
ALOX15 P16050 1/20 0.30
FDPS P14324 1/20 0.30
PTPN2 P17706 1/20 0.30
PTPN1 P18031 1/20 0.30
PTPRA P18433 1/20 0.30
PTPRB P23467 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5081776 0.93 SLC6A2 (0.42) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL813617 0.87 SLC6A2 (0.46) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5078348 0.85 SLC6A2 (0.34) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5077245 0.85 SLC6A2 (0.34) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5077386 0.85 SLC6A2 (0.38) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5081510 0.85 SLC6A2 (0.34) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5075153 0.83 SLC6A2 (0.35) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5078189 0.83 SLC6A2 (0.35) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5078220 0.83 SLC6A2 (0.35) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5078138 0.83 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US claimed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed