SCHEMBL5078348

SCHEMBL5078348

COCC(CO[Si](C)(C)Cc1ccccc1)(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.34
TAAR1 Q96RJ0 1/20 0.34
LMNA P02545 1/20 0.33
CYP2D6 P10635 1/20 0.33
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5081767 0.94 TAAR1 (0.38) SLC6A2TAAR1LMNACYP2D6NR1H2
SCHEMBL5081510 0.88 SLC6A2 (0.34) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5077173 0.85 SLC6A2 (0.37) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5075137 0.85 L3MBTL1 (0.34) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5077300 0.85 ALDH1A1 (0.33) SLC6A2TAAR1LMNACYP2D6NR1H2
SCHEMBL5078138 0.85 SLC6A2 (0.33) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5077729 0.84 TAAR1 (0.30) TAAR1
SCHEMBL813617 0.83 SLC6A2 (0.46) SLC6A2TAAR1LMNACYP2D6CYP1A2
SCHEMBL5080807 0.82 KMT2A (0.32)
SCHEMBL5078143 0.82 MAPT (0.31) SLC6A2TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US claimed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US claimed
US-7399812-B2 Silicon ether compounds and a method for the preparation thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-07-15 US disclosed
US-7323431-B2 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2008-01-29 US disclosed
US-20060183873-A1 Silicon ether compounds and a method for the preparation thereof BEIJING RESEARCH INSTITUTE OF CHEMICAL INDUSTRY, CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2006-08-17 US disclosed
US-20060142146-A1 Catalyst for olefin polymerization and use of the same CHINA PETROLEUM & CHEMICAL CORPORATION 2006-06-29 US disclosed