Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 5/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.53 |
| ▸ | GSR | P00390 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788370 | 0.87 | GABRA1 (0.47) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL2415959 | 0.80 | HSD17B10 (0.50) | MAPTLMNATHRBIGF1RALOX15 | |
| SCHEMBL4603030 | 0.78 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL200138 | 0.77 | GABRA1 (0.60) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL6417176 | 0.76 | GABRA1 (0.58) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9181982 | 0.76 | GABRA1 (0.54) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL4595014 | 0.75 | GSR (0.55) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9177990 | 0.74 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9183829 | 0.74 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 | |
| SCHEMBL9181950 | 0.74 | GABRA1 (0.53) | GABRA1GABRB1GABRB2GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996538-A1 | METHOD FOR PREPARATION OF AROMATIC CHLOROFORMATES | Sabic Innovative Plastics IP B.V. (NL) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007001757-A1 | METHOD FOR PREPARATION OF AROMATIC CHLOROFORMATES | GENERAL ELECTRIC COMPANY (US) | 2007-01-04 | — | — | WO | disclosed |