Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.54 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.54 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.53 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.53 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.53 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049696 | 0.83 | GSR (0.59) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL13057520 | 0.81 | GSR (0.57) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL4594369 | 0.79 | GSR (0.55) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL2467528 | 0.78 | GSR (0.63) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL11810825 | 0.78 | GSR (0.53) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL200138 | 0.78 | GABRA1 (0.60) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL6419829 | 0.78 | GSR (0.53) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL11519193 | 0.77 | TRPA1 (0.52) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL5692077 | 0.76 | GABRA1 (0.54) | GSRGABRA1GABRB1GABRB2GABRA5 | |
| SCHEMBL9193416 | 0.76 | GABRA1 (0.54) | GSRGABRA1GABRB1GABRB2GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463187-A | Process for the preparation of 3,5-dihydrocarbyl-4-hydroxybenzylmalonic acid esters | ETHYL CORPORATION (US) | 1984-07-31 | — | — | US | claimed |
| EP-1945705-A1 | PHOTOLATENT SYSTEMS | Ciba Holding Inc. (CH) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007054446-A1 | PHOTOLATENT SYSTEMS | CIBA HOLDING INC. (CH) | 2007-05-18 | — | — | WO | disclosed |
| EP-0163635-A4 | PROCESS FOR PREPARING SUBSTITUTED BENZYL MALONIC ACID ESTERS. | ETHYL CORP (US) | 1986-04-02 | — | — | EP | disclosed |
| EP-0163635-A1 | PROCESS FOR PREPARING SUBSTITUTED BENZYL MALONIC ACID ESTERS | ETHYL CORPORATION (US) | 1985-12-11 | — | — | EP | disclosed |
| WO-1985002182-A1 | PROCESS FOR PREPARING SUBSTITUTED BENZYL MALONIC ACID ESTERS | ETHYL CORPORATION (US) | 1985-05-23 | — | — | WO | disclosed |
| US-4463187-A | Process for the preparation of 3,5-dihydrocarbyl-4-hydroxybenzylmalonic acid esters | ETHYL CORPORATION (US) | 1984-07-31 | — | — | US | disclosed |