Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 2/20 | 0.34 |
| ▸ | PTPRC | P08575 | 2/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1687150 | 0.84 | AKT1 (0.42) | ALDH1A1GAARAB9AFFAR1CTSB | |
| SCHEMBL1686904 | 0.74 | NPC1 (0.45) | ALDH1A1GAARAB9ANPC1L3MBTL1 | |
| SCHEMBL4200404 | 0.73 | ALDH1A1 (0.53) | ALDH1A1GAARAB9AFFAR1CTSB | |
| SCHEMBL1686997 | 0.70 | PDK1 (0.43) | ALDH1A1GAAFFAR1CTSBELANE | |
| SCHEMBL3901459 | 0.70 | NPC1 (0.42) | ALDH1A1GAARAB9ANPC1FFAR1 | |
| SCHEMBL1686999 | 0.68 | KMT2A (0.44) | ALDH1A1GAARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL1686957 | 0.68 | DGAT1 (0.47) | ALDH1A1GAARAB9ANPC1L3MBTL1 | |
| SCHEMBL5284350 | 0.67 | GAA (0.63) | ALDH1A1GAARAB9ANPC1FFAR1 | |
| SCHEMBL3589217 | 0.67 | ALDH1A1 (0.41) | ALDH1A1GAARAB9ANPC1ELANE | |
| SCHEMBL1687186 | 0.66 | KMT2A (0.41) | ALDH1A1GAARAB9ANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1965798-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | Basilea Pharmaceutica AG (CH) | 2008-09-10 | — | — | EP | disclosed |
| WO-2007065288-A2 | USEFUL COMBINATIONS OF MONOBACTAM ANTIBIOTICS WITH BETA-LACTAMASE INHIBITORS | BASILEA PHARMACEUTICA AG (CH) | 2007-06-14 | — | — | WO | disclosed |