SCHEMBL507792

SCHEMBL507792

Clc1ccc(Cl)c(N=C=Nc2cc(Cl)ccc2Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 3/20 0.46
TSHR P16473 5/20 0.41
CYP3A4 P08684 4/20 0.41
TDP1 Q9NUW8 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HSD17B10 Q99714 2/20 0.41
MAPK1 P28482 2/20 0.39
CYP1A2 P05177 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C19 P33261 1/20 0.39
HPGD P15428 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CASP3 P42574 1/20 0.37
SENP7 Q9BQF6 1/20 0.37
SENP6 Q9GZR1 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.35
ITGB3 P05106 1/20 0.33
ITGAV P06756 1/20 0.33
SIGMAR1 Q99720 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30585174 1.00 TP53 (0.46) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL29507682 0.82 TDP1 (0.50) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL1020285 0.82 TP53 (0.42) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL27771939 0.82 TP53 (0.42) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL785906 0.82 TDP1 (0.50) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL11492006 0.81 TP53 (0.46) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL15188822 0.76 CYP3A4 (0.46) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL8943122 0.76 TDP1 (0.44) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL11349652 0.73 TP53 (0.48) TP53TSHRCYP3A4TDP1ALDH1A1
SCHEMBL11709272 0.73 TP53 (0.48) TP53TSHRCYP3A4TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180134947-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER TECHNOLOGY CORPORATION 2018-05-17 US claimed
WO-2016159817-A1 METHODS FOR TREATING HIGH TEMPERATURE SUBTERRANEAN FORMATIONS SCHLUMBERGER CANADA LIMITED (CA) 2016-10-06 WO claimed
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles 3M INNOVATIVE PROPERTIES COMPANY (US) 2026-02-24 US disclosed
US-20240294748-A1 FILM COMPRISING POLYLACTIC ACID POLYMER SUITABLE FOR GRAPHIC ARTICLES 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-09-05 US disclosed
US-12065531-B2 Polyglycolic acid resin and production process thereof PUJING CHEMICAL INDUSTRY CO., LTD. (CN) 2024-08-20 US disclosed
WO-2024143405-A1 METHOD FOR PRODUCING RESIN FOR RECYCLING 花王株式会社 2024-07-04 WO disclosed
CN-116234846-B Resin composition and molded article 株式会社可乐丽 2024-07-02 CN disclosed
CN-113574104-B Method for improving tracking resistance of thermoplastic resin 宝理塑料株式会社 2024-06-18 CN disclosed
WO-2024111181-A1 THERMOSETTING RESIN COMPOSITION AND CURED PRODUCT ポリプラ・エボニック株式会社 2024-05-30 WO disclosed
CN-115427515-B Resin composition for galvanometer type laser welding, molded article, set for galvanometer type laser welding, in-vehicle camera component, in-vehicle camera module, ultraviolet exposure body, and method for producing molded article 三菱化学株式会社 2024-05-24 CN disclosed
WO-2024101133-A1 FLAME RETARDANT POLYESTER ELASTOMER RESIN COMPOSITION 東洋紡エムシー株式会社 2024-05-16 WO disclosed
US-7268190-B2 Resin composition comprising polylactic acid and polyacetal and a molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2007-09-11 US disclosed
US-20070184264-A1 Flame-retardant polyester artificial hair KANEKA CORPORATION (JP) 2007-08-09 US disclosed
EP-1792941-A1 RESIN COMPOSITION AND MOLDED ARTICLE COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2007-06-06 EP disclosed
US-20060079638-A1 Polybutylene terephthalate resin composition WINTECH POLYMER LTD. (JP) 2006-04-13 US disclosed
US-20040242803-A1 Resin composition and molded article, film, and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2004-12-02 US disclosed
EP-1445282-A1 RESIN COMPOSITION AND MOLDED ARTICLE FILM AND FIBER EACH COMPRISING THE SAME TORAY INDUSTRIES, INC. (JP) 2004-08-11 EP disclosed
US-5866672-A HALOGEN FLAME RETARDANT, EPOXY COMPOUNDS OR CARBODIIMIDE COMPOUNDS AND AN ANTIMONY COMPOUND KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-02-02 US disclosed
EP-0763567-A1 FLAME-RETARDANT POLYETHYLENE TEREPHTHALATE RESIN COMPOSITIONS Kanegafuchi Kagaku Kogyo Kabushiki Kaisha (JP) 1997-03-19 EP disclosed
US-3975329-A HYDROLYTIC AND THERMAL STABILITY THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12065531-B2 Polyglycolic acid resin and production process thereof RPN2, RIOX2, RPN1 TP53 2809/4885TSHR 3962/4885CYP3A4 3649/4885
US-12559624-B2 Film comprising polylactic acid polymer suitable for graphic articles POT1, PARG, TCP1 TP53 963/4885TSHR 1619/4885CYP3A4 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.