Sugi Predict

Sugi Predict / Compounds / SCHEMBL785906

SCHEMBL785906

SCHEMBL785906

O=C=Nc1cc(Cl)ccc1Cl

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 4/20 0.50
▸ MAPK1 P28482 1/20 0.50
▸ TP53 P04637 3/20 0.42
▸ HPGD P15428 3/20 0.40
▸ SMN1; SMN2 Q16637 3/20 0.40
▸ CYP3A4 P08684 6/20 0.39
▸ TRPA1 O75762 1/20 0.38
▸ TSHR P16473 5/20 0.38
▸ ALDH1A1 P00352 4/20 0.38
▸ HSD17B10 Q99714 2/20 0.38
▸ MAPT P10636 3/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ CTDSP1 Q9GZU7 1/20 0.36
▸ MEN1 O00255 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ CASP1 P29466 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29507682 1.00 TDP1 (0.50) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL8943122 0.92 TDP1 (0.44) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL8592899 0.88 TDP1 (0.41) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL30111366 0.84 TDP1 (0.42) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL10316536 0.84 TDP1 (0.42) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL227614 0.83 TDP1 (0.45) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL29862788 0.83 TDP1 (0.45) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL30585174 0.82 TP53 (0.46) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL507792 0.82 TP53 (0.46) TDP1MAPK1TP53HPGDSMN1; SMN2
SCHEMBL49899 0.81 TDP1 (0.70) TDP1MAPK1HPGDCYP3A4TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117700188-A Self-cleaning fiber-reinforced internal-hydrophobic anti-slip wear-resistant porous concrete pavement material 山东高速建设管理集团有限公司 2024-03-15 — — CN claimed
CN-111471171-B Arylsulfonic acid intermediate, preparation method thereof and application of aryl sulfonic acid intermediate in synthesizing low-temperature-sensitivity additive for concrete 江苏苏博特新材料股份有限公司 2023-07-18 — — CN claimed
CN-106892893-B Method for preparing lactide from lactic acid oligomer 中国科学院长春应用化学研究所 2020-09-25 — — CN claimed
CN-111471171-A Aryl sulfonic acid intermediate, preparation method thereof and application thereof in synthesizing low-temperature-sensitivity additive for concrete 江苏苏博特新材料股份有限公司 2020-07-31 — — CN claimed
CN-109776481-A A kind of preparation method of high chemical purity lactide 青岛凯玉盈商贸有限公司 2019-05-21 — — CN claimed
CN-106810677-B Preparation method, the preparation method of polymer grade lactide of poly-lactic acid in high molecular weight 中国科学院长春应用化学研究所 2019-04-26 — — CN claimed
CN-108440977-A Modified pitch, modifying agent and preparation method for high-modulus Rut resistance concrete 长安大学 2018-08-24 — — CN claimed
CN-106810677-A The preparation method of poly-lactic acid in high molecular weight, the preparation method of polymer grade lactide 中国科学院长春应用化学研究所 2017-06-09 — — CN claimed
CN-105330640-A Preparation method for high chemical purity lactide CHANGCHUN APPLIED CHEMISTRY 2016-02-17 — — CN claimed
CN-103304446-B Derivatization method of optically active phenylacetylene compound UNIV HARBIN ENG 2015-02-25 — — CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 — — EP claimed
US-3940246-A Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor CIBA-GEIGY AG (CH) 1976-02-24 — — US claimed
US-20250289782-A1 THIOL COMPOUND AND USES THEREOF SHIKOKU CHEMICALS CORPORATION (JP) 2025-09-18 — — US disclosed
WO-2025121227-A1 CURABLE COMPOSITION, CURED PRODUCT, ADHESIVE, AND SEALANT 四国化成工業株式会社 2025-06-12 — — WO disclosed
EP-4524130-A1 THIOL COMPOUND AND USES THEREOF Shikoku Chemicals Corporation (JP) 2025-03-19 — — EP disclosed
EP-4524174-A1 CURING AGENT AND USE THEREOF Shikoku Chemicals Corporation (JP) 2025-03-19 — — EP disclosed
US-3958933-A Process for the manufacture of fast dyeings on synthetic hydrophobic textile material CIBA-GEIGY CORPORATION (US) 1976-06-01 — — US disclosed
US-3948009-A Sound insulating wall made from composite rubber material BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 — — US disclosed
US-3940246-A Sublimation transfer and isocyanate fixation of amino- or hydroxy-containing dyestuffs and transfer sheets therefor CIBA-GEIGY AG (CH) 1976-02-24 — — US disclosed
US-3932318-A COPOLYMERS WITH ISOCYANATES, CRYOGENIC POLYMERIZATION, NONFLAMMABLE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250289782-A1 THIOL COMPOUND AND USES THEREOF TMT1A, TXN, CTH TDP1 3067/4885MAPK1 4473/4885TP53 4033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.